Detailed information NTG0418989

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: IBC08_RS07585
• Genome accession: NZ_CP061019
• Coordinates: 1467719..1469818 (-)
• Length: 699 a.a.
• NCBI ID: WP_207563285.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 24853
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1462719..1474818

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBC08_RS07555 (IBC08_07530)	pptB	1463185..1464222 (-)	1038	WP_179971023.1	ABC transporter permease	Regulator
IBC08_RS07560 (IBC08_07535)	pptA	1464219..1464950 (-)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
IBC08_RS07565 (IBC08_07540)	-	1465015..1465434 (+)	420	WP_002951675.1	HIT family protein	-
IBC08_RS07570 (IBC08_07545)	-	1465431..1465739 (+)	309	WP_179971427.1	hypothetical protein	-
IBC08_RS10075	-	1466291..1466461 (-)	171	WP_011226439.1	hypothetical protein	-
IBC08_RS07580 (IBC08_07555)	-	1466531..1467166 (-)	636	WP_179971026.1	DUF4230 domain-containing protein	-
IBC08_RS10265	-	1467185..1467310 (-)	126	WP_011681534.1	hypothetical protein	-
IBC08_RS07585 (IBC08_07560)	clpE	1467719..1469818 (-)	2100	WP_207563285.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
IBC08_RS07590 (IBC08_07565)	-	1470533..1471624 (-)	1092	WP_179971027.1	nucleotidyltransferase	-
IBC08_RS07595 (IBC08_07570)	-	1471631..1472371 (-)	741	WP_277426406.1	class I SAM-dependent methyltransferase	-
IBC08_RS07600 (IBC08_07575)	rsfS	1472696..1473049 (-)	354	WP_011227491.1	ribosome silencing factor	-
IBC08_RS07605 (IBC08_07580)	yqeK	1473073..1473663 (-)	591	WP_002951696.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
IBC08_RS07610 (IBC08_07585)	-	1473660..1474292 (-)	633	WP_002951698.1	nicotinate-nucleotide adenylyltransferase	-
IBC08_RS07615 (IBC08_07590)	yhbY	1474396..1474713 (-)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77178.04 Da
• Isoelectric Point: 4.8556

>NTDB_id=418989 IBC08_RS07585 WP_207563285.1 1467719..1469818(-) (clpE) [Streptococcus thermophilus strain 24853]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLSRNLT
QEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQIIGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQHPV
TDVNAVEHEIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKNAK

Nucleotide

• Length: 2100 bp

>NTDB_id=418989 IBC08_RS07585 WP_207563285.1 1467719..1469818(-) (clpE) [Streptococcus thermophilus strain 24853]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACGCAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTAGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTTGGCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGCAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTATTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAATACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACATGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAAATGCTAAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• AAA lid domain (AAA_lid_9) (255-349)

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.724	100	0.469
clpC	Lactococcus lactis subsp. cremoris KW2	48.75	91.559	0.446
clpE	Streptococcus pneumoniae Rx1	48.499	90.558	0.439
clpE	Streptococcus pneumoniae D39	48.499	90.558	0.439
clpE	Streptococcus pneumoniae R6	48.499	90.558	0.439
clpE	Streptococcus pneumoniae TIGR4	48.418	90.415	0.438
clpC	Bacillus subtilis subsp. subtilis str. 168	46.285	92.418	0.428
clpC	Streptococcus thermophilus LMD-9	43.417	91.273	0.396
clpC	Streptococcus thermophilus LMG 18311	43.26	91.273	0.395
clpC	Streptococcus pneumoniae TIGR4	43.339	89.127	0.386
clpC	Streptococcus pneumoniae Rx1	43.339	89.127	0.386
clpC	Streptococcus pneumoniae D39	43.339	89.127	0.386
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.598	88.269	0.385
clpC	Streptococcus mutans UA159	42.788	89.27	0.382