Detailed information NTG0418432

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: GWG04_RS10990
• Genome accession: NZ_CP047922
• Coordinates: 2221460..2222347 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain SR231
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2216460..2227347

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GWG04_RS10960 (GWG04_10995)	-	2217192..2217953 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
GWG04_RS10965 (GWG04_11000)	-	2218198..2218653 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
GWG04_RS14750	-	2218775..2218876 (+)	102	WP_000731976.1	SE2200 family small protein	-
GWG04_RS10975 (GWG04_11010)	-	2218936..2220360 (-)	1425	WP_000953755.1	alkaline phosphatase	-
GWG04_RS10980 (GWG04_11015)	-	2220558..2220758 (+)	201	WP_000604730.1	hypothetical protein	-
GWG04_RS10985 (GWG04_11020)	braR	2220784..2221449 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
GWG04_RS10990 (GWG04_11025)	braS	2221460..2222347 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
GWG04_RS10995 (GWG04_11030)	-	2222455..2223210 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
GWG04_RS11000 (GWG04_11035)	-	2223207..2225207 (+)	2001	WP_000776751.1	ABC transporter permease	-
GWG04_RS11005 (GWG04_11040)	-	2225866..2225979 (+)	114	Protein_2145	hypothetical protein	-
GWG04_RS11010 (GWG04_11045)	-	2226361..2226621 (+)	261	WP_001791974.1	hypothetical protein	-
GWG04_RS11015 (GWG04_11050)	-	2226631..2227128 (+)	498	WP_001065268.1	glutathione peroxidase	-
GWG04_RS11020 (GWG04_11055)	-	2227236..2227328 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=418432 GWG04_RS10990 WP_000143425.1 2221460..2222347(+) (braS) [Staphylococcus aureus strain SR231]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=418432 GWG04_RS10990 WP_000143425.1 2221460..2222347(+) (braS) [Staphylococcus aureus strain SR231]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1