Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   GV831_RS01765 Genome accession   NZ_CP047891
Coordinates   353271..354746 (+) Length   491 a.a.
NCBI ID   WP_010906048.1    Uniprot ID   A0A2A9ICZ0
Organism   Lactococcus lactis subsp. lactis strain WHH2311     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 348271..359746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GV831_RS01730 (GV831_01710) - 348533..349369 (+) 837 WP_014570661.1 metallophosphoesterase -
  GV831_RS01735 (GV831_01715) - 349463..349960 (+) 498 WP_226898137.1 CHAP domain-containing protein -
  GV831_RS01740 (GV831_01720) - 350445..350807 (+) 363 WP_010906050.1 TIGR02328 family protein -
  GV831_RS01745 (GV831_01725) - 350889..351353 (+) 465 WP_003130761.1 hypothetical protein -
  GV831_RS01750 (GV831_01730) - 351509..351754 (+) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  GV831_RS01755 (GV831_01735) - 351885..352415 (+) 531 WP_003130758.1 DUF177 domain-containing protein -
  GV831_RS01760 (GV831_01740) covR 352571..353263 (+) 693 WP_003130756.1 response regulator transcription factor Regulator
  GV831_RS01765 (GV831_01745) covS 353271..354746 (+) 1476 WP_010906048.1 HAMP domain-containing histidine kinase Regulator
  GV831_RS01770 (GV831_01750) - 354928..356169 (+) 1242 WP_014570660.1 ammonium transporter -
  GV831_RS01775 (GV831_01755) - 356301..356642 (+) 342 WP_010906046.1 P-II family nitrogen regulator -
  GV831_RS01780 (GV831_01760) murD 357133..358485 (+) 1353 WP_003130748.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56195.08 Da        Isoelectric Point: 4.8253

>NTDB_id=418330 GV831_RS01765 WP_010906048.1 353271..354746(+) (covS) [Lactococcus lactis subsp. lactis strain WHH2311]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLSILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=418330 GV831_RS01765 WP_010906048.1 353271..354746(+) (covS) [Lactococcus lactis subsp. lactis strain WHH2311]
ATGAAAAAACTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATCAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCTAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCATGTTTACAATGATATGATGTTGAAGATGAAGGCATATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCATGAATTAAGAACACCTTTAGCTGTCTTGGATGGACATATTAACTTGTTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGCCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGGTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTCTGAGGATGAACAGTTTGTGATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAGCGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTATCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

ArlS sensor domain (ArlS_N)

(54-185)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

HAMP domain (HAMP)

(208-258)

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2A9ICZ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

100

100

1

Multiple sequence alignment