Detailed information NTG0418082

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3S63_RS10650
• Genome accession: NZ_CP047863
• Coordinates: 2166797..2167684 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain UP_1106
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2161797..2172684

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S63_RS10620 (E3S63_10620)	-	2162529..2163290 (+)	762	WP_000323441.1	alpha/beta hydrolase	-
E3S63_RS10625 (E3S63_10625)	-	2163535..2163990 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3S63_RS14365	-	2164112..2164213 (+)	102	WP_000731976.1	SE2200 family small protein	-
E3S63_RS10635 (E3S63_10635)	-	2164273..2165697 (-)	1425	WP_000953755.1	alkaline phosphatase	-
E3S63_RS10640 (E3S63_10640)	-	2165895..2166095 (+)	201	WP_000604730.1	hypothetical protein	-
E3S63_RS10645 (E3S63_10645)	braR	2166121..2166786 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3S63_RS10650 (E3S63_10650)	braS	2166797..2167684 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3S63_RS10655 (E3S63_10655)	-	2167792..2168547 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3S63_RS10660 (E3S63_10660)	-	2168544..2170544 (+)	2001	WP_000776750.1	ABC transporter permease	-
E3S63_RS10665 (E3S63_10665)	-	2171203..2171316 (+)	114	Protein_2064	hypothetical protein	-
E3S63_RS10670 (E3S63_10670)	-	2171698..2171958 (+)	261	WP_001791974.1	hypothetical protein	-
E3S63_RS10675 (E3S63_10675)	-	2171968..2172465 (+)	498	WP_001065268.1	glutathione peroxidase	-
E3S63_RS10680 (E3S63_10680)	-	2172573..2172665 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=418082 E3S63_RS10650 WP_000143425.1 2166797..2167684(+) (braS) [Staphylococcus aureus strain UP_1106]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=418082 E3S63_RS10650 WP_000143425.1 2166797..2167684(+) (braS) [Staphylococcus aureus strain UP_1106]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1