Detailed information NTG0417906

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3S68_RS10940
• Genome accession: NZ_CP047854
• Coordinates: 2209217..2210104 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain UP_1525
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2204217..2215104

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S68_RS10910 (E3S68_10910)	-	2204949..2205710 (+)	762	WP_000323441.1	alpha/beta hydrolase	-
E3S68_RS10915 (E3S68_10915)	-	2205955..2206410 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3S68_RS14705	-	2206532..2206633 (+)	102	WP_000731976.1	SE2200 family small protein	-
E3S68_RS10925 (E3S68_10925)	-	2206693..2208117 (-)	1425	WP_000953755.1	alkaline phosphatase	-
E3S68_RS10930 (E3S68_10930)	-	2208315..2208515 (+)	201	WP_000604730.1	hypothetical protein	-
E3S68_RS10935 (E3S68_10935)	braR	2208541..2209206 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3S68_RS10940 (E3S68_10940)	braS	2209217..2210104 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3S68_RS10945 (E3S68_10945)	-	2210212..2210967 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3S68_RS10950 (E3S68_10950)	-	2210964..2212964 (+)	2001	WP_000776750.1	ABC transporter permease	-
E3S68_RS10955 (E3S68_10955)	-	2213623..2213736 (+)	114	Protein_2126	hypothetical protein	-
E3S68_RS10960 (E3S68_10960)	-	2214118..2214378 (+)	261	WP_001791974.1	hypothetical protein	-
E3S68_RS10965 (E3S68_10965)	-	2214388..2214885 (+)	498	WP_001065268.1	glutathione peroxidase	-
E3S68_RS10970 (E3S68_10970)	-	2214993..2215085 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=417906 E3S68_RS10940 WP_000143425.1 2209217..2210104(+) (braS) [Staphylococcus aureus strain UP_1525]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=417906 E3S68_RS10940 WP_000143425.1 2209217..2210104(+) (braS) [Staphylococcus aureus strain UP_1525]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1