Detailed information NTG0417864

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3S71_RS10350
• Genome accession: NZ_CP047852
• Coordinates: 2108342..2109229 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain UP_274
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2103342..2114229

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S71_RS10320 (E3S71_10320)	-	2104074..2104835 (+)	762	WP_000323453.1	alpha/beta hydrolase	-
E3S71_RS10325 (E3S71_10325)	-	2105080..2105535 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3S71_RS14025	-	2105657..2105758 (+)	102	WP_000731976.1	SE2200 family small protein	-
E3S71_RS10335 (E3S71_10335)	-	2105818..2107242 (-)	1425	WP_000953734.1	alkaline phosphatase	-
E3S71_RS10340 (E3S71_10340)	-	2107440..2107640 (+)	201	WP_000604727.1	hypothetical protein	-
E3S71_RS10345 (E3S71_10345)	braR	2107666..2108331 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3S71_RS10350 (E3S71_10350)	braS	2108342..2109229 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3S71_RS10355 (E3S71_10355)	-	2109337..2110092 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3S71_RS10360 (E3S71_10360)	-	2110089..2112089 (+)	2001	WP_000776751.1	ABC transporter permease	-
E3S71_RS10365 (E3S71_10365)	-	2112748..2112861 (+)	114	WP_011447078.1	hypothetical protein	-
E3S71_RS10370 (E3S71_10370)	-	2113243..2113503 (+)	261	WP_001789307.1	hypothetical protein	-
E3S71_RS10375 (E3S71_10375)	-	2113513..2114010 (+)	498	WP_001065271.1	glutathione peroxidase	-
E3S71_RS10380 (E3S71_10380)	-	2114118..2114201 (-)	84	WP_031797553.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=417864 E3S71_RS10350 WP_000143419.1 2108342..2109229(+) (braS) [Staphylococcus aureus strain UP_274]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=417864 E3S71_RS10350 WP_000143419.1 2108342..2109229(+) (braS) [Staphylococcus aureus strain UP_274]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997