Detailed information NTG0417660

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3S83_RS13350
• Genome accession: NZ_CP047843
• Coordinates: 2679409..2680296 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain UP_620
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2674409..2685296

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S83_RS13320 (E3S83_13320)	-	2674428..2674520 (+)	93	WP_010956583.1	hypothetical protein	-
E3S83_RS13325 (E3S83_13325)	-	2674628..2675125 (-)	498	WP_001065268.1	glutathione peroxidase	-
E3S83_RS13330 (E3S83_13330)	-	2675135..2675395 (-)	261	WP_001791974.1	hypothetical protein	-
E3S83_RS13335 (E3S83_13335)	-	2675777..2675890 (-)	114	Protein_2597	hypothetical protein	-
E3S83_RS13340 (E3S83_13340)	-	2676549..2678549 (-)	2001	WP_000776740.1	ABC transporter permease	-
E3S83_RS13345 (E3S83_13345)	-	2678546..2679301 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3S83_RS13350 (E3S83_13350)	braS	2679409..2680296 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3S83_RS13355 (E3S83_13355)	braR	2680307..2680972 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3S83_RS13360 (E3S83_13360)	-	2680998..2681198 (-)	201	WP_000604727.1	hypothetical protein	-
E3S83_RS13365 (E3S83_13365)	-	2681396..2682820 (+)	1425	WP_000953748.1	alkaline phosphatase	-
E3S83_RS14180	-	2682880..2682981 (-)	102	WP_000731972.1	SE2200 family small protein	-
E3S83_RS13375 (E3S83_13375)	-	2683103..2683558 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3S83_RS13380 (E3S83_13380)	-	2683803..2684564 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=417660 E3S83_RS13350 WP_000143417.1 2679409..2680296(-) (braS) [Staphylococcus aureus strain UP_620]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=417660 E3S83_RS13350 WP_000143417.1 2679409..2680296(-) (braS) [Staphylococcus aureus strain UP_620]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99