Detailed information NTG0417487

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3S91_RS10330
• Genome accession: NZ_CP047835
• Coordinates: 2115102..2115989 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain UP_883
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2110102..2120989

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S91_RS10300 (E3S91_10300)	-	2110834..2111595 (+)	762	WP_000323453.1	alpha/beta hydrolase	-
E3S91_RS10305 (E3S91_10305)	-	2111840..2112295 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3S91_RS14015	-	2112417..2112518 (+)	102	WP_000731976.1	SE2200 family small protein	-
E3S91_RS10315 (E3S91_10315)	-	2112578..2114002 (-)	1425	WP_000953734.1	alkaline phosphatase	-
E3S91_RS10320 (E3S91_10320)	-	2114200..2114400 (+)	201	WP_000604727.1	hypothetical protein	-
E3S91_RS10325 (E3S91_10325)	braR	2114426..2115091 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3S91_RS10330 (E3S91_10330)	braS	2115102..2115989 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3S91_RS10335 (E3S91_10335)	-	2116097..2116852 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3S91_RS10340 (E3S91_10340)	-	2116849..2118849 (+)	2001	WP_000776751.1	ABC transporter permease	-
E3S91_RS10345 (E3S91_10345)	-	2119508..2119621 (+)	114	WP_011447078.1	hypothetical protein	-
E3S91_RS10350 (E3S91_10350)	-	2120003..2120263 (+)	261	WP_001789307.1	hypothetical protein	-
E3S91_RS10355 (E3S91_10355)	-	2120273..2120770 (+)	498	WP_001065271.1	glutathione peroxidase	-
E3S91_RS10360 (E3S91_10360)	-	2120878..2120961 (-)	84	WP_031797553.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=417487 E3S91_RS10330 WP_000143419.1 2115102..2115989(+) (braS) [Staphylococcus aureus strain UP_883]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=417487 E3S91_RS10330 WP_000143419.1 2115102..2115989(+) (braS) [Staphylococcus aureus strain UP_883]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997