Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE   Type   Machinery gene
Locus tag   E3S92_RS02325 Genome accession   NZ_CP047833
Coordinates   437246..437545 (+) Length   99 a.a.
NCBI ID   WP_000844413.1    Uniprot ID   X5E258
Organism   Staphylococcus aureus strain UP_926     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 432246..442545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S92_RS02285 (E3S92_02285) - 432307..432510 (+) 204 WP_000087561.1 YqgQ family protein -
  E3S92_RS02290 (E3S92_02290) - 432507..433493 (+) 987 WP_000161307.1 ROK family glucokinase -
  E3S92_RS02295 (E3S92_02295) - 433493..433822 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  E3S92_RS02300 (E3S92_02300) - 433819..434442 (+) 624 WP_001223009.1 MBL fold metallo-hydrolase -
  E3S92_RS02305 (E3S92_02305) comGA 434494..435468 (+) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  E3S92_RS02310 (E3S92_02310) comGB 435440..436510 (+) 1071 WP_000776409.1 competence type IV pilus assembly protein ComGB Machinery gene
  E3S92_RS02315 (E3S92_02315) comGC 436524..436835 (+) 312 WP_000472255.1 competence type IV pilus major pilin ComGC Machinery gene
  E3S92_RS02320 (E3S92_02320) comGD 436813..437259 (+) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  E3S92_RS02325 (E3S92_02325) comGE 437246..437545 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  E3S92_RS02330 (E3S92_02330) comGF 437463..437960 (+) 498 WP_001796472.1 competence type IV pilus minor pilin ComGF Machinery gene
  E3S92_RS02335 (E3S92_02335) - 438057..438203 (+) 147 WP_001789879.1 hypothetical protein -
  E3S92_RS02340 (E3S92_02340) - 438193..438717 (+) 525 WP_001015120.1 shikimate kinase -
  E3S92_RS02345 (E3S92_02345) gcvT 438876..439967 (+) 1092 WP_000093344.1 glycine cleavage system aminomethyltransferase GcvT -
  E3S92_RS02350 (E3S92_02350) gcvPA 439987..441333 (+) 1347 WP_000019698.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence


Protein


Download         Length: 99 a.a.        Molecular weight: 11093.20 Da        Isoelectric Point: 9.9215

>NTDB_id=417425 E3S92_RS02325 WP_000844413.1 437246..437545(+) (comGE) [Staphylococcus aureus strain UP_926]
MKSYKCKGSFLIDSMAGFLLIGLITLLLIPMMNQMQASINHKLQTIDASKVILTTVSKINKEELKKGVTIGKYDIKQSDQ
QICAISKNTTSYQKTCIQY

Nucleotide


Download         Length: 300 bp        

>NTDB_id=417425 E3S92_RS02325 WP_000844413.1 437246..437545(+) (comGE) [Staphylococcus aureus strain UP_926]
ATGAAAAGCTATAAGTGTAAAGGATCATTCTTAATAGATAGTATGGCTGGATTTTTGCTAATTGGATTGATTACATTACT
ATTGATACCAATGATGAATCAAATGCAAGCGAGTATAAACCATAAACTACAAACAATTGATGCTTCTAAAGTAATTTTGA
CGACTGTATCTAAAATTAATAAAGAAGAACTTAAGAAGGGGGTAACTATAGGGAAATATGATATTAAGCAAAGTGACCAA
CAAATATGTGCCATTTCAAAAAATACCACTTCTTATCAAAAGACATGTATACAGTATTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB X5E258

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Staphylococcus aureus MW2

86.842

100

1

  comGE Staphylococcus aureus N315

98.99

100

0.99


Multiple sequence alignment