Detailed information NTG0417409

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: E3S92_RS00485
• Genome accession: NZ_CP047833
• Coordinates: 90194..91237 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UP_926
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 85194..96237

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S92_RS00455 (E3S92_00455)	-	85762..85871 (+)	110	Protein_93	hypothetical protein	-
E3S92_RS00460 (E3S92_00460)	-	85900..86313 (+)	414	WP_001622129.1	hypothetical protein	-
E3S92_RS00465 (E3S92_00465)	-	86491..87477 (-)	987	WP_000999713.1	FUSC family protein	-
E3S92_RS00470 (E3S92_00470)	map	88120..88878 (+)	759	WP_000636137.1	type I methionyl aminopeptidase	-
E3S92_RS00475 (E3S92_00475)	-	89095..89481 (+)	387	WP_001110184.1	hypothetical protein	-
E3S92_RS00480 (E3S92_00480)	liaF	89496..90197 (+)	702	WP_160190094.1	cell wall-active antibiotics response protein LiaF	-
E3S92_RS00485 (E3S92_00485)	vraS	90194..91237 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
E3S92_RS00490 (E3S92_00490)	vraR	91227..91856 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
E3S92_RS00495 (E3S92_00495)	-	91969..93186 (-)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
E3S92_RS00500 (E3S92_00500)	-	93464..93739 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
E3S92_RS00505 (E3S92_00505)	-	93746..94210 (-)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
E3S92_RS00510 (E3S92_00510)	-	94357..94557 (+)	201	WP_000180459.1	DUF1128 family protein	-
E3S92_RS00515 (E3S92_00515)	-	94626..95816 (+)	1191	WP_411896787.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=417409 E3S92_RS00485 WP_001017131.1 90194..91237(+) (vraS) [Staphylococcus aureus strain UP_926]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=417409 E3S92_RS00485 WP_001017131.1 90194..91237(+) (vraS) [Staphylococcus aureus strain UP_926]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1