Detailed information NTG0417407

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3S94_RS13040
• Genome accession: NZ_CP047830
• Coordinates: 2626554..2627441 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain UP_996
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2621554..2632441

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S94_RS13010 (E3S94_13010)	-	2621573..2621665 (+)	93	WP_010956583.1	hypothetical protein	-
E3S94_RS13015 (E3S94_13015)	-	2621773..2622270 (-)	498	WP_001065268.1	glutathione peroxidase	-
E3S94_RS13020 (E3S94_13020)	-	2622280..2622540 (-)	261	WP_001789910.1	hypothetical protein	-
E3S94_RS13025 (E3S94_13025)	-	2622922..2623035 (-)	114	WP_001791776.1	hypothetical protein	-
E3S94_RS13030 (E3S94_13030)	-	2623694..2625694 (-)	2001	WP_000776751.1	ABC transporter permease	-
E3S94_RS13035 (E3S94_13035)	-	2625691..2626446 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3S94_RS13040 (E3S94_13040)	braS	2626554..2627441 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3S94_RS13045 (E3S94_13045)	braR	2627452..2628117 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3S94_RS13050 (E3S94_13050)	-	2628143..2628343 (-)	201	WP_000604728.1	hypothetical protein	-
E3S94_RS13055 (E3S94_13055)	-	2628541..2629965 (+)	1425	WP_000953744.1	alkaline phosphatase	-
E3S94_RS13825	-	2630025..2630126 (-)	102	WP_000731972.1	SE2200 family small protein	-
E3S94_RS13065 (E3S94_13065)	-	2630248..2630703 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3S94_RS13070 (E3S94_13070)	-	2630948..2631709 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=417407 E3S94_RS13040 WP_000143419.1 2626554..2627441(-) (braS) [Staphylococcus aureus strain UP_996]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=417407 E3S94_RS13040 WP_000143419.1 2626554..2627441(-) (braS) [Staphylococcus aureus strain UP_996]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997