Detailed information NTG0417321

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3T01_RS10200
• Genome accession: NZ_CP047826
• Coordinates: 2096485..2097372 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain UP_1239
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2091485..2102372

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3T01_RS10170 (E3T01_10170)	-	2092217..2092978 (+)	762	WP_000323448.1	alpha/beta hydrolase	-
E3T01_RS10175 (E3T01_10175)	-	2093223..2093678 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3T01_RS13850	-	2093800..2093901 (+)	102	WP_000731972.1	SE2200 family small protein	-
E3T01_RS10185 (E3T01_10185)	-	2093961..2095385 (-)	1425	WP_160181644.1	alkaline phosphatase	-
E3T01_RS10190 (E3T01_10190)	-	2095583..2095783 (+)	201	WP_000604727.1	hypothetical protein	-
E3T01_RS10195 (E3T01_10195)	braR	2095809..2096474 (+)	666	WP_000697887.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3T01_RS10200 (E3T01_10200)	braS	2096485..2097372 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3T01_RS10205 (E3T01_10205)	-	2097480..2098235 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3T01_RS10210 (E3T01_10210)	-	2098232..2100232 (+)	2001	WP_000776733.1	ABC transporter permease	-
E3T01_RS10215 (E3T01_10215)	-	2100891..2101004 (+)	114	WP_011447078.1	hypothetical protein	-
E3T01_RS10220 (E3T01_10220)	-	2101386..2101646 (+)	261	WP_001789307.1	hypothetical protein	-
E3T01_RS10225 (E3T01_10225)	-	2101656..2102153 (+)	498	WP_001065268.1	glutathione peroxidase	-
E3T01_RS10230 (E3T01_10230)	-	2102261..2102344 (-)	84	WP_031797553.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=417321 E3T01_RS10200 WP_000143419.1 2096485..2097372(+) (braS) [Staphylococcus aureus strain UP_1239]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=417321 E3T01_RS10200 WP_000143419.1 2096485..2097372(+) (braS) [Staphylococcus aureus strain UP_1239]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997