Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E3T09_RS13265 Genome accession   NZ_CP047813
Coordinates   2694813..2695529 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain UP_1500     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2689813..2700529
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3T09_RS13245 (E3T09_13245) - 2690905..2691855 (+) 951 WP_043044119.1 LacI family DNA-binding transcriptional regulator -
  E3T09_RS13250 (E3T09_13250) - 2692004..2693488 (+) 1485 WP_043044120.1 sucrose-6-phosphate hydrolase -
  E3T09_RS13255 (E3T09_13255) - 2693485..2694444 (+) 960 WP_043044121.1 carbohydrate kinase family protein -
  E3T09_RS13260 (E3T09_13260) - 2694632..2694741 (-) 110 Protein_2567 hypothetical protein -
  E3T09_RS13265 (E3T09_13265) agrA 2694813..2695529 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  E3T09_RS13270 (E3T09_13270) agrC 2695548..2696840 (-) 1293 WP_001789596.1 quorum-sensing sensor histidine kinase AgrC -
  E3T09_RS13275 (E3T09_13275) agrD 2696865..2697005 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  E3T09_RS13280 (E3T09_13280) agrB 2697002..2697571 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  E3T09_RS13795 hld 2697861..2697941 (+) 81 WP_000046022.1 delta-hemolysin -
  E3T09_RS13290 (E3T09_13290) - 2698541..2699326 (-) 786 WP_043044123.1 carbon-nitrogen family hydrolase -
  E3T09_RS13295 (E3T09_13295) - 2699687..2700313 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=417118 E3T09_RS13265 WP_000688492.1 2694813..2695529(-) (agrA) [Staphylococcus aureus strain UP_1500]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=417118 E3T09_RS13265 WP_000688492.1 2694813..2695529(-) (agrA) [Staphylococcus aureus strain UP_1500]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment