Detailed information NTG0417024

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3T14_RS09245
• Genome accession: NZ_CP047809
• Coordinates: 1832299..1833186 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain UP_1591
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1827299..1838186

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3T14_RS09215 (E3T14_09230)	-	1827318..1827410 (+)	93	WP_010956583.1	hypothetical protein	-
E3T14_RS09220 (E3T14_09235)	-	1827518..1828015 (-)	498	WP_001065268.1	glutathione peroxidase	-
E3T14_RS09225 (E3T14_09240)	-	1828025..1828285 (-)	261	WP_001789910.1	hypothetical protein	-
E3T14_RS09230 (E3T14_09245)	-	1828667..1828780 (-)	114	WP_011447078.1	hypothetical protein	-
E3T14_RS09235 (E3T14_09250)	-	1829439..1831439 (-)	2001	WP_000776751.1	ABC transporter permease	-
E3T14_RS09240 (E3T14_09255)	-	1831436..1832191 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3T14_RS09245 (E3T14_09260)	braS	1832299..1833186 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3T14_RS09250 (E3T14_09265)	braR	1833197..1833862 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3T14_RS09255 (E3T14_09270)	-	1833888..1834088 (-)	201	WP_000604728.1	hypothetical protein	-
E3T14_RS09260 (E3T14_09275)	-	1834286..1835710 (+)	1425	WP_000953744.1	alkaline phosphatase	-
E3T14_RS09265 (E3T14_09280)	-	1835780..1835890 (+)	111	WP_001791296.1	hypothetical protein	-
E3T14_RS09270 (E3T14_09285)	-	1835993..1836448 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3T14_RS09275 (E3T14_09290)	-	1836693..1837454 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=417024 E3T14_RS09245 WP_000143419.1 1832299..1833186(-) (braS) [Staphylococcus aureus strain UP_1591]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=417024 E3T14_RS09245 WP_000143419.1 1832299..1833186(-) (braS) [Staphylococcus aureus strain UP_1591]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997