Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E3T15_RS13070 Genome accession   NZ_CP047807
Coordinates   2648327..2649043 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain UP_1612     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2643327..2654043
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3T15_RS13050 (E3T15_13050) - 2644411..2645361 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  E3T15_RS13055 (E3T15_13055) - 2645510..2646994 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  E3T15_RS13060 (E3T15_13060) - 2646991..2647950 (+) 960 WP_001253314.1 carbohydrate kinase family protein -
  E3T15_RS13065 (E3T15_13065) - 2648138..2648247 (-) 110 Protein_2541 hypothetical protein -
  E3T15_RS13070 (E3T15_13070) agrA 2648327..2649043 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  E3T15_RS13075 (E3T15_13075) agrC 2649062..2650345 (-) 1284 WP_000447889.1 quorum-sensing sensor histidine kinase AgrC -
  E3T15_RS13080 (E3T15_13080) agrD 2650375..2650518 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  E3T15_RS13085 (E3T15_13085) - 2650521..2651084 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  E3T15_RS13710 hld 2651375..2651455 (+) 81 WP_000046022.1 delta-hemolysin -
  E3T15_RS13095 (E3T15_13095) - 2652052..2652837 (-) 786 Protein_2547 carbon-nitrogen family hydrolase -
  E3T15_RS13100 (E3T15_13100) - 2653198..2653824 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=416992 E3T15_RS13070 WP_000688498.1 2648327..2649043(-) (agrA) [Staphylococcus aureus strain UP_1612]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=416992 E3T15_RS13070 WP_000688498.1 2648327..2649043(-) (agrA) [Staphylococcus aureus strain UP_1612]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment