Detailed information NTG0416904

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3S60_RS10605
• Genome accession: NZ_CP047804
• Coordinates: 2169646..2170533 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain UP_774
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2164646..2175533

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S60_RS10575 (E3S60_10575)	-	2165378..2166139 (+)	762	WP_000323441.1	alpha/beta hydrolase	-
E3S60_RS10580 (E3S60_10580)	-	2166384..2166839 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3S60_RS14190	-	2166961..2167062 (+)	102	WP_000731976.1	SE2200 family small protein	-
E3S60_RS10590 (E3S60_10590)	-	2167122..2168546 (-)	1425	WP_000953755.1	alkaline phosphatase	-
E3S60_RS10595 (E3S60_10595)	-	2168744..2168944 (+)	201	WP_000604730.1	hypothetical protein	-
E3S60_RS10600 (E3S60_10600)	braR	2168970..2169635 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3S60_RS10605 (E3S60_10605)	braS	2169646..2170533 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3S60_RS10610 (E3S60_10610)	-	2170641..2171396 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3S60_RS10615 (E3S60_10615)	-	2171393..2173393 (+)	2001	WP_000776750.1	ABC transporter permease	-
E3S60_RS10620 (E3S60_10620)	-	2174052..2174165 (+)	114	Protein_2053	hypothetical protein	-
E3S60_RS10625 (E3S60_10625)	-	2174547..2174807 (+)	261	WP_001791974.1	hypothetical protein	-
E3S60_RS10630 (E3S60_10630)	-	2174817..2175314 (+)	498	WP_001065268.1	glutathione peroxidase	-
E3S60_RS10635 (E3S60_10635)	-	2175422..2175514 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=416904 E3S60_RS10605 WP_000143425.1 2169646..2170533(+) (braS) [Staphylococcus aureus strain UP_774]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=416904 E3S60_RS10605 WP_000143425.1 2169646..2170533(+) (braS) [Staphylococcus aureus strain UP_774]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1