Detailed information NTG0416890

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: E3S60_RS05545
• Genome accession: NZ_CP047804
• Coordinates: 1098451..1099437 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain UP_774
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1093451..1104437

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S60_RS05520 (E3S60_05520)	-	1093711..1094058 (-)	348	WP_001242103.1	hypothetical protein	-
E3S60_RS05525 (E3S60_05525)	-	1094244..1094837 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
E3S60_RS05530 (E3S60_05530)	-	1094941..1095306 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
E3S60_RS05535 (E3S60_05535)	yjbH	1095329..1096135 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
E3S60_RS05540 (E3S60_05540)	pepF	1096595..1098403 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
E3S60_RS05545 (E3S60_05545)	coiA	1098451..1099437 (-)	987	WP_000959282.1	competence protein CoiA	Machinery gene
E3S60_RS05550 (E3S60_05550)	mecA	1099558..1100277 (-)	720	WP_001217728.1	adaptor protein MecA	-
E3S60_RS05555 (E3S60_05555)	spxA	1100648..1101043 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
E3S60_RS05560 (E3S60_05560)	trpS	1101337..1102326 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
E3S60_RS05565 (E3S60_05565)	opp4C	1102368..1103249 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
E3S60_RS05570 (E3S60_05570)	opp4B	1103261..1104223 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=416890 E3S60_RS05545 WP_000959282.1 1098451..1099437(-) (coiA) [Staphylococcus aureus strain UP_774]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=416890 E3S60_RS05545 WP_000959282.1 1098451..1099437(-) (coiA) [Staphylococcus aureus strain UP_774]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976