Detailed information NTG0416822

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: E3S62_RS00445
• Genome accession: NZ_CP047803
• Coordinates: 80717..81760 (+)
• Length: 347 a.a.
• NCBI ID: WP_160199679.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain UP_1097
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 75717..86760

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S62_RS00415 (E3S62_00415)	-	76397..76506 (+)	110	Protein_84	hypothetical protein	-
E3S62_RS00420 (E3S62_00420)	-	76535..76948 (+)	414	WP_001622129.1	hypothetical protein	-
E3S62_RS00425 (E3S62_00425)	-	77126..78112 (-)	987	WP_000999713.1	FUSC family protein	-
E3S62_RS00430 (E3S62_00430)	map	78643..79401 (+)	759	WP_000636137.1	type I methionyl aminopeptidase	-
E3S62_RS00435 (E3S62_00435)	-	79618..80004 (+)	387	WP_001110184.1	hypothetical protein	-
E3S62_RS00440 (E3S62_00440)	liaF	80019..80720 (+)	702	WP_160200267.1	cell wall-active antibiotics response protein LiaF	-
E3S62_RS00445 (E3S62_00445)	vraS	80717..81760 (+)	1044	WP_160199679.1	sensor histidine kinase	Regulator
E3S62_RS00450 (E3S62_00450)	vraR	81750..82379 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
E3S62_RS00455 (E3S62_00455)	-	82492..83709 (-)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
E3S62_RS00460 (E3S62_00460)	-	83987..84262 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
E3S62_RS00465 (E3S62_00465)	-	84269..84733 (-)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
E3S62_RS00470 (E3S62_00470)	-	84880..85080 (+)	201	WP_000180459.1	DUF1128 family protein	-
E3S62_RS00475 (E3S62_00475)	-	85149..86339 (+)	1191	WP_411896787.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40072.57 Da
• Isoelectric Point: 6.0577

>NTDB_id=416822 E3S62_RS00445 WP_160199679.1 80717..81760(+) (vraS) [Staphylococcus aureus strain UP_1097]
MNHYIRTIGSMLILVYSMLAVFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=416822 E3S62_RS00445 WP_160199679.1 80717..81760(+) (vraS) [Staphylococcus aureus strain UP_1097]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGTATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997