Detailed information NTG0416809

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: E3S67_RS08320
• Genome accession: NZ_CP047802
• Coordinates: 1649800..1650843 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UP_1442
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1644800..1655843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S67_RS08290 (E3S67_08290)	-	1645221..1646477 (-)	1257	WP_001795108.1	aminopeptidase	-
E3S67_RS08295 (E3S67_08295)	-	1646480..1646680 (-)	201	WP_000180460.1	DUF1128 family protein	-
E3S67_RS08300 (E3S67_08300)	-	1646827..1647291 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
E3S67_RS08305 (E3S67_08305)	-	1647298..1647573 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
E3S67_RS08310 (E3S67_08310)	-	1647851..1649068 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
E3S67_RS08315 (E3S67_08315)	vraR	1649181..1649810 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
E3S67_RS08320 (E3S67_08320)	vraS	1649800..1650843 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
E3S67_RS08325 (E3S67_08325)	liaF	1650840..1651541 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
E3S67_RS08330 (E3S67_08330)	-	1651556..1651942 (-)	387	WP_001110179.1	hypothetical protein	-
E3S67_RS08335 (E3S67_08335)	map	1652159..1652917 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
E3S67_RS08340 (E3S67_08340)	-	1653448..1654434 (+)	987	WP_000999717.1	FUSC family protein	-
E3S67_RS08345 (E3S67_08345)	-	1654865..1655278 (-)	414	WP_001557448.1	hypothetical protein	-
E3S67_RS08350 (E3S67_08350)	-	1655307..1655417 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=416809 E3S67_RS08320 WP_001017131.1 1649800..1650843(-) (vraS) [Staphylococcus aureus strain UP_1442]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=416809 E3S67_RS08320 WP_001017131.1 1649800..1650843(-) (vraS) [Staphylococcus aureus strain UP_1442]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1