Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   E3S70_RS11195 Genome accession   NZ_CP047801
Coordinates   2268759..2269424 (+) Length   221 a.a.
NCBI ID   WP_000697879.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UP_248     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2263759..2274424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S70_RS11170 (E3S70_11170) - 2265167..2265928 (+) 762 WP_000323448.1 alpha/beta hydrolase -
  E3S70_RS11175 (E3S70_11175) - 2266173..2266628 (+) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  E3S70_RS14910 - 2266750..2266851 (+) 102 WP_000731972.1 SE2200 family small protein -
  E3S70_RS11185 (E3S70_11185) - 2266911..2268335 (-) 1425 WP_000953743.1 alkaline phosphatase -
  E3S70_RS11190 (E3S70_11190) - 2268533..2268733 (+) 201 WP_000604727.1 hypothetical protein -
  E3S70_RS11195 (E3S70_11195) braR 2268759..2269424 (+) 666 WP_000697879.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  E3S70_RS11200 (E3S70_11200) braS 2269435..2270322 (+) 888 WP_000143418.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  E3S70_RS11205 (E3S70_11205) - 2270430..2271185 (+) 756 WP_000923764.1 ABC transporter ATP-binding protein -
  E3S70_RS11210 (E3S70_11210) - 2271182..2273182 (+) 2001 WP_000776744.1 ABC transporter permease -
  E3S70_RS11215 (E3S70_11215) - 2273858..2273971 (+) 114 WP_014937089.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25388.46 Da        Isoelectric Point: 4.7961

>NTDB_id=416770 E3S70_RS11195 WP_000697879.1 2268759..2269424(+) (braR) [Staphylococcus aureus strain UP_248]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQSIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=416770 E3S70_RS11195 WP_000697879.1 2268759..2269424(+) (braR) [Staphylococcus aureus strain UP_248]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAGCCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAGCATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995

Multiple sequence alignment