Detailed information NTG0416729

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3S72_RS10735
• Genome accession: NZ_CP047800
• Coordinates: 2166663..2167550 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain UP_296
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2161663..2172550

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S72_RS10705 (E3S72_10705)	-	2162395..2163156 (+)	762	WP_000323441.1	alpha/beta hydrolase	-
E3S72_RS10710 (E3S72_10710)	-	2163401..2163856 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3S72_RS14320	-	2163978..2164079 (+)	102	WP_000731976.1	SE2200 family small protein	-
E3S72_RS10720 (E3S72_10720)	-	2164139..2165563 (-)	1425	WP_160198897.1	alkaline phosphatase	-
E3S72_RS10725 (E3S72_10725)	-	2165761..2165961 (+)	201	WP_000604730.1	hypothetical protein	-
E3S72_RS10730 (E3S72_10730)	braR	2165987..2166652 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3S72_RS10735 (E3S72_10735)	braS	2166663..2167550 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3S72_RS10740 (E3S72_10740)	-	2167658..2168413 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E3S72_RS10745 (E3S72_10745)	-	2168410..2170410 (+)	2001	WP_000776751.1	ABC transporter permease	-
E3S72_RS10750 (E3S72_10750)	-	2171069..2171182 (+)	114	Protein_2086	hypothetical protein	-
E3S72_RS10755 (E3S72_10755)	-	2171564..2171824 (+)	261	WP_001791974.1	hypothetical protein	-
E3S72_RS10760 (E3S72_10760)	-	2171834..2172331 (+)	498	WP_001065268.1	glutathione peroxidase	-
E3S72_RS10765 (E3S72_10765)	-	2172439..2172531 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=416729 E3S72_RS10735 WP_000143425.1 2166663..2167550(+) (braS) [Staphylococcus aureus strain UP_296]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=416729 E3S72_RS10735 WP_000143425.1 2166663..2167550(+) (braS) [Staphylococcus aureus strain UP_296]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1