Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   H9W85_RS22395 Genome accession   NZ_CP060703
Coordinates   4841789..4844638 (+) Length   949 a.a.
NCBI ID   WP_023101526.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain NRD619     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 4836789..4849638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H9W85_RS22365 (H9W85_22365) - 4836944..4838038 (-) 1095 WP_023101523.1 IS5 family transposase -
  H9W85_RS22370 (H9W85_22370) - 4838423..4839502 (+) 1080 WP_023101524.1 IS5 family transposase -
  H9W85_RS29850 (H9W85_22375) - 4839836..4840109 (+) 274 Protein_4440 IS66 family transposase zinc-finger binding domain-containing protein -
  H9W85_RS29980 - 4840231..4840464 (-) 234 Protein_4441 IS110 family transposase -
  H9W85_RS22385 (H9W85_22385) - 4840809..4841090 (+) 282 WP_012761384.1 helix-turn-helix domain-containing protein -
  H9W85_RS22390 (H9W85_22390) - 4841126..4841695 (+) 570 WP_023101525.1 Hsp20/alpha crystallin family protein -
  H9W85_RS22395 (H9W85_22395) clpC 4841789..4844638 (+) 2850 WP_023101526.1 heat shock survival AAA family ATPase ClpK Regulator
  H9W85_RS22400 (H9W85_22400) cls 4844655..4846085 (+) 1431 WP_023101527.1 cardiolipin synthase -
  H9W85_RS22405 (H9W85_22405) ftsH 4846113..4847942 (+) 1830 WP_023101528.1 ATP-dependent zinc metalloprotease FtsH -
  H9W85_RS22410 (H9W85_22410) hsp20-GI 4848021..4848479 (+) 459 WP_019485624.1 small heat shock protein sHSP20-GI -
  H9W85_RS22415 (H9W85_22415) yfdX1 4848501..4849409 (+) 909 WP_021567662.1 heat resistance protein YfdX1 -

Sequence

Protein


Download         Length: 949 a.a.        Molecular weight: 104358.28 Da        Isoelectric Point: 5.7316

>NTDB_id=416655 H9W85_RS22395 WP_023101526.1 4841789..4844638(+) (clpC) [Pseudomonas aeruginosa strain NRD619]
MARKQCQVCGQPATVRVEANLNGRHSTMLLCDDHYRQLVRQQKRTVSPLEALFGSRSGLFEDFLGSDFFRIGDDAPSMAA
DTDEVVDASFGEPAPAGTGTARRRGSGLASRISEQSEALLQEAAKHAAEFGRPEVDTEHLLLALSDSDVVKTILGQFKIK
VDDLKRQIESEAKRGDKPFEGEIGVSPRVKDALSRAFVASNELGHSYVGPEHFLIGLAEEGEGLAANLLRRYGLTPQALR
QQVSKVVGKGAEDGRAETPTNTPELDKYSRDLTKMAREGKLDPVIGRAQEIETTIEVLARRKKNNPVLIGEPGVGKTAIV
EGLAQRMVAGEVPETLRDKRLVELNINAMVAGAKYRGEFEERVQKVLKEVTEHQGELILFIDEVHTIVGAGQGGGEGGLD
VANVFKPMMARGELNLIGATTLNEYQKYIEKDAALERRFQPVMVPEPTVAQTMMILRGLRDTFEAHHKVSITEDAIIAAA
ELSDRYITARFLPDKAIDLLDQAAARVKLSATARPVAVQELESELHQLRREQDYVAARKQYDQAAELGKRIEAKEAELKK
LVEEWERERASGSAEVKAEHVAQIVSRLTGIPVNELTVEEREKLLHLEQRLHERLVGQDEAVRAVADAVRLSRAGLREGG
KPVATFLFLGPTGVGKTELAKALAESIYGDEGALLRIDMSEYGERHTVARLVGAPPGYVGYDEGGQLTEKVRRKPYSVLL
LDEIEKAHPDVYNILLQVFDDGRLTDGKGRVVDFTNTIIIATSNLGSDIIQRRLKARGAAGEEYEKTKSEVMDVLRGHFR
PEFLNRIDEIIVFHALGKEEIRHIVGLQLDRVARNAASQGVTLTFDQTLIDHFAEEGYKPEFGARELKRLIRSELETALA
REMLGGGIGKADHASARWDDKAERVVFERQEPAAQPAEPEKPDAANVAEAPPNGESKPARKKKSAGGGS

Nucleotide


Download         Length: 2850 bp        

>NTDB_id=416655 H9W85_RS22395 WP_023101526.1 4841789..4844638(+) (clpC) [Pseudomonas aeruginosa strain NRD619]
ATGGCCAGAAAACAATGCCAAGTCTGCGGCCAGCCCGCCACGGTGCGGGTGGAAGCCAATCTCAATGGTCGCCACAGCAC
CATGCTGTTGTGTGACGATCACTATCGCCAACTGGTGCGCCAGCAAAAGCGCACCGTCTCACCGCTGGAAGCCTTGTTCG
GCTCGCGCAGCGGGCTGTTCGAAGACTTCCTTGGCAGCGACTTCTTCCGCATCGGTGACGACGCACCGTCCATGGCGGCC
GATACCGACGAGGTCGTCGATGCCTCGTTCGGCGAACCCGCGCCGGCCGGTACGGGCACCGCGCGCCGTCGCGGCAGTGG
GCTCGCCAGCCGTATCAGCGAACAGTCCGAGGCCCTATTGCAGGAGGCCGCCAAACATGCCGCCGAATTTGGCCGCCCCG
AAGTCGATACCGAACACCTGCTGCTGGCGCTATCCGACAGCGACGTGGTCAAGACCATCCTGGGGCAGTTCAAGATCAAG
GTCGATGACCTCAAGCGCCAGATCGAATCCGAAGCCAAGCGCGGCGATAAGCCGTTCGAGGGCGAGATCGGCGTGTCGCC
CCGGGTCAAGGACGCGCTCAGCCGTGCTTTCGTGGCCTCCAACGAACTCGGCCACTCTTATGTCGGGCCGGAGCATTTCC
TGATCGGGCTCGCCGAGGAAGGCGAAGGTTTGGCGGCCAACCTGCTGCGCCGTTACGGCCTCACGCCGCAAGCGCTGCGC
CAGCAGGTAAGCAAGGTGGTCGGCAAAGGGGCCGAGGATGGCCGCGCCGAGACGCCGACCAACACGCCGGAACTCGACAA
GTATTCGCGCGACCTCACCAAGATGGCGCGCGAGGGCAAGCTCGATCCGGTCATCGGCCGCGCGCAGGAGATCGAGACGA
CCATCGAAGTGCTGGCCCGGCGCAAGAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCGGCAAGACCGCCATCGTC
GAAGGGCTGGCGCAGCGCATGGTCGCCGGCGAAGTGCCCGAGACGCTGCGCGACAAGCGCCTGGTGGAACTCAACATCAA
TGCCATGGTGGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAGCGCGTGCAGAAGGTGCTCAAGGAAGTGACCGAGCACC
AGGGCGAGCTGATTCTCTTCATCGACGAAGTGCACACCATCGTCGGTGCAGGCCAGGGTGGCGGCGAAGGCGGGCTGGAC
GTGGCCAACGTGTTCAAGCCGATGATGGCGCGCGGCGAACTGAACCTGATCGGCGCCACCACGCTCAACGAGTATCAGAA
GTACATCGAGAAGGACGCCGCGCTGGAGCGTCGCTTCCAGCCGGTGATGGTGCCCGAGCCGACGGTAGCGCAGACCATGA
TGATCCTGCGCGGCCTGCGCGACACCTTCGAGGCGCACCACAAGGTCAGCATCACCGAGGATGCGATCATCGCCGCCGCC
GAGTTGTCGGACCGCTACATCACCGCGCGCTTTTTGCCTGACAAGGCCATCGACCTGCTCGACCAGGCGGCCGCGCGCGT
CAAGCTGTCGGCCACGGCCCGGCCGGTGGCCGTGCAGGAGCTGGAGTCCGAACTGCACCAGCTGCGGCGTGAACAGGATT
ACGTGGCCGCGCGCAAGCAGTACGACCAGGCCGCCGAGCTCGGCAAGCGCATCGAAGCCAAGGAGGCCGAGCTCAAGAAG
CTCGTCGAGGAATGGGAACGCGAGCGCGCCTCGGGCAGCGCCGAAGTCAAGGCCGAGCATGTCGCGCAGATCGTCTCGCG
CCTGACCGGCATTCCGGTCAACGAGCTGACGGTGGAAGAACGCGAGAAGCTGCTGCATCTGGAGCAGCGGCTGCACGAGC
GCCTGGTGGGCCAGGACGAAGCAGTACGTGCCGTGGCCGATGCCGTGCGGCTGTCGCGCGCGGGCCTGCGCGAAGGCGGC
AAGCCAGTGGCCACCTTCCTGTTCCTCGGGCCGACGGGTGTGGGCAAGACCGAACTCGCCAAGGCACTGGCCGAGTCCAT
CTATGGCGATGAGGGCGCGCTGCTGCGCATCGACATGTCCGAGTACGGTGAACGCCATACCGTGGCACGCTTGGTGGGCG
CGCCTCCGGGTTATGTGGGCTATGACGAGGGCGGCCAGCTCACCGAGAAGGTGCGTCGCAAACCCTACAGCGTGTTGTTG
CTCGATGAGATCGAAAAAGCGCACCCCGACGTCTACAACATCCTGCTGCAGGTATTCGACGACGGGCGGCTCACCGACGG
CAAGGGCCGGGTGGTGGATTTCACCAATACCATCATCATCGCCACCTCGAACTTGGGCTCGGACATCATCCAGCGTCGGC
TGAAGGCCCGTGGCGCCGCCGGCGAGGAATACGAGAAGACCAAGTCCGAGGTGATGGACGTGCTGCGCGGACACTTCCGC
CCCGAGTTCCTCAACCGCATCGACGAGATCATCGTCTTCCATGCGCTGGGTAAGGAGGAGATCCGCCATATCGTCGGCCT
GCAGCTCGATCGTGTGGCCCGCAACGCCGCCAGCCAGGGCGTGACGTTGACCTTCGACCAGACCTTGATCGACCACTTCG
CGGAGGAAGGCTACAAACCCGAGTTCGGCGCGCGCGAGCTCAAGCGGCTGATCCGCAGCGAGCTGGAAACCGCGCTGGCA
CGCGAGATGCTCGGTGGTGGCATCGGCAAGGCCGATCACGCCAGCGCCCGCTGGGATGACAAGGCCGAACGGGTGGTCTT
CGAGCGCCAGGAGCCAGCCGCGCAGCCGGCCGAGCCTGAAAAGCCCGATGCAGCGAACGTGGCCGAGGCACCGCCGAACG
GCGAGAGCAAGCCTGCGCGCAAGAAGAAGTCAGCGGGCGGCGGATCTTGA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(816-894)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(123-171)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(199-248)

AAA domain (Cdc48 subfamily) (AAA_2)

(641-810)

AAA lid domain (AAA_lid_9)

(449-547)

ATPase family associated with various cellular activities (AAA) (AAA)

(307-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Bacillus subtilis subsp. subtilis str. 168

50.442

83.351

0.42
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.542

85.669

0.373
  clpC Streptococcus thermophilus LMD-9

42.373

87.039

0.369
  clpC Streptococcus thermophilus LMG 18311

42.284

86.723

0.367
  clpC Streptococcus pneumoniae Rx1

42.241

85.564

0.361
  clpC Streptococcus pneumoniae D39

42.241

85.564

0.361

Multiple sequence alignment