Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E3S75_RS13375 Genome accession   NZ_CP047798
Coordinates   2717731..2718447 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain UP_378     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2712731..2723447
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S75_RS13355 (E3S75_13355) - 2713823..2714773 (+) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -
  E3S75_RS13360 (E3S75_13360) - 2714922..2716406 (+) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  E3S75_RS13365 (E3S75_13365) - 2716403..2717362 (+) 960 WP_001253295.1 carbohydrate kinase family protein -
  E3S75_RS13370 (E3S75_13370) - 2717552..2717659 (-) 108 WP_031785433.1 hypothetical protein -
  E3S75_RS13375 (E3S75_13375) agrA 2717731..2718447 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  E3S75_RS13380 (E3S75_13380) agrC 2718466..2719758 (-) 1293 WP_201750752.1 quorum-sensing sensor histidine kinase AgrC -
  E3S75_RS13385 (E3S75_13385) agrD 2719783..2719923 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  E3S75_RS13390 (E3S75_13390) agrB 2719920..2720489 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  E3S75_RS13755 hld 2720778..2720858 (+) 81 WP_000046022.1 delta-hemolysin -
  E3S75_RS13400 (E3S75_13400) - 2721459..2722244 (-) 786 WP_000867944.1 carbon-nitrogen family hydrolase -
  E3S75_RS13405 (E3S75_13405) - 2722605..2723231 (-) 627 WP_000522375.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=416651 E3S75_RS13375 WP_000688492.1 2717731..2718447(-) (agrA) [Staphylococcus aureus strain UP_378]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=416651 E3S75_RS13375 WP_000688492.1 2717731..2718447(-) (agrA) [Staphylococcus aureus strain UP_378]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment