Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E3S77_RS13550 Genome accession   NZ_CP047797
Coordinates   2774998..2775714 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain UP_426     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2769998..2780714
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S77_RS13530 (E3S77_13530) - 2771092..2772042 (+) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -
  E3S77_RS13535 (E3S77_13535) - 2772191..2773675 (+) 1485 WP_000141423.1 sucrose-6-phosphate hydrolase -
  E3S77_RS13540 (E3S77_13540) - 2773672..2774631 (+) 960 WP_047213656.1 carbohydrate kinase family protein -
  E3S77_RS13545 (E3S77_13545) - 2774819..2774926 (-) 108 WP_031927410.1 hypothetical protein -
  E3S77_RS13550 (E3S77_13550) agrA 2774998..2775714 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  E3S77_RS13555 (E3S77_13555) agrC 2775733..2777025 (-) 1293 WP_201747116.1 quorum-sensing sensor histidine kinase AgrC -
  E3S77_RS13560 (E3S77_13560) agrD 2777050..2777190 (-) 141 WP_001094303.1 cyclic lactone autoinducer peptide AgrD -
  E3S77_RS13565 (E3S77_13565) - 2777192..2777755 (-) 564 WP_001105716.1 accessory gene regulator AgrB -
  E3S77_RS13570 (E3S77_13570) hld 2778046..2778126 (+) 81 WP_000046023.1 delta-hemolysin -
  E3S77_RS13575 (E3S77_13575) - 2778724..2779509 (-) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  E3S77_RS13580 (E3S77_13580) - 2779861..2780487 (-) 627 WP_000522380.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=416609 E3S77_RS13550 WP_000688492.1 2774998..2775714(-) (agrA) [Staphylococcus aureus strain UP_426]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=416609 E3S77_RS13550 WP_000688492.1 2774998..2775714(-) (agrA) [Staphylococcus aureus strain UP_426]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCAAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCAGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment