Detailed information NTG0416520

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: E3S79_RS09255
• Genome accession: NZ_CP047795
• Coordinates: 1900107..1901150 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UP_490
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1895107..1906150

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S79_RS09225 (E3S79_09225)	-	1895528..1896775 (-)	1248	WP_000656302.1	aminopeptidase	-
E3S79_RS09230 (E3S79_09230)	-	1896787..1896987 (-)	201	WP_000180459.1	DUF1128 family protein	-
E3S79_RS09235 (E3S79_09235)	-	1897134..1897598 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
E3S79_RS09240 (E3S79_09240)	-	1897605..1897880 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
E3S79_RS09245 (E3S79_09245)	-	1898158..1899375 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
E3S79_RS09250 (E3S79_09250)	vraR	1899488..1900117 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
E3S79_RS09255 (E3S79_09255)	vraS	1900107..1901150 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
E3S79_RS09260 (E3S79_09260)	liaF	1901147..1901848 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
E3S79_RS09265 (E3S79_09265)	-	1901863..1902249 (-)	387	WP_001110184.1	hypothetical protein	-
E3S79_RS09270 (E3S79_09270)	map	1902466..1903224 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
E3S79_RS09275 (E3S79_09275)	-	1903811..1904797 (+)	987	WP_000999713.1	FUSC family protein	-
E3S79_RS09280 (E3S79_09280)	-	1904975..1905388 (-)	414	WP_001622129.1	hypothetical protein	-
E3S79_RS09285 (E3S79_09285)	-	1905417..1905526 (-)	110	Protein_1795	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=416520 E3S79_RS09255 WP_001017131.1 1900107..1901150(-) (vraS) [Staphylococcus aureus strain UP_490]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=416520 E3S79_RS09255 WP_001017131.1 1900107..1901150(-) (vraS) [Staphylococcus aureus strain UP_490]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1