Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E3S81_RS13745 Genome accession   NZ_CP047794
Coordinates   2800680..2801396 (-) Length   238 a.a.
NCBI ID   WP_160199154.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UP_551     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2795680..2806396
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S81_RS13725 (E3S81_13725) - 2796774..2797724 (+) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -
  E3S81_RS13730 (E3S81_13730) - 2797873..2799357 (+) 1485 WP_000141423.1 sucrose-6-phosphate hydrolase -
  E3S81_RS13735 (E3S81_13735) - 2799354..2800313 (+) 960 WP_047213656.1 carbohydrate kinase family protein -
  E3S81_RS13740 (E3S81_13740) - 2800501..2800608 (-) 108 WP_031927410.1 hypothetical protein -
  E3S81_RS13745 (E3S81_13745) agrA 2800680..2801396 (-) 717 WP_160199154.1 quorum-sensing response regulator AgrA Regulator
  E3S81_RS13750 (E3S81_13750) agrC 2801415..2802707 (-) 1293 WP_001807128.1 quorum-sensing sensor histidine kinase AgrC -
  E3S81_RS13755 (E3S81_13755) agrD 2802732..2802872 (-) 141 WP_160199155.1 cyclic lactone autoinducer peptide AgrD -
  E3S81_RS13760 (E3S81_13760) - 2802874..2803437 (-) 564 WP_001105716.1 accessory gene regulator AgrB -
  E3S81_RS13765 (E3S81_13765) hld 2803728..2803808 (+) 81 WP_000046023.1 delta-hemolysin -
  E3S81_RS13770 (E3S81_13770) - 2804406..2805191 (-) 786 WP_106459828.1 carbon-nitrogen family hydrolase -
  E3S81_RS13775 (E3S81_13775) - 2805543..2806169 (-) 627 WP_000522380.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27922.89 Da        Isoelectric Point: 6.0927

>NTDB_id=416485 E3S81_RS13745 WP_160199154.1 2800680..2801396(-) (agrA) [Staphylococcus aureus strain UP_551]
MKIFICEDDSKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNNFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=416485 E3S81_RS13745 WP_160199154.1 2800680..2801396(-) (agrA) [Staphylococcus aureus strain UP_551]
ATGAAAATTTTCATTTGCGAAGACGATTCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAACTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCAAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCAGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.16

100

0.992

Multiple sequence alignment