Detailed information NTG0416399

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E3S88_RS11690
• Genome accession: NZ_CP047792
• Coordinates: 2332860..2333747 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain UP_794
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2327860..2338747

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S88_RS11660 (E3S88_11660)	-	2327873..2327965 (+)	93	WP_031918515.1	hypothetical protein	-
E3S88_RS11665 (E3S88_11665)	-	2328073..2328570 (-)	498	WP_001065267.1	glutathione peroxidase	-
E3S88_RS11670 (E3S88_11670)	-	2328580..2328840 (-)	261	WP_001791974.1	hypothetical protein	-
E3S88_RS11675 (E3S88_11675)	-	2329222..2329335 (-)	114	WP_072468803.1	hypothetical protein	-
E3S88_RS11680 (E3S88_11680)	-	2330000..2332000 (-)	2001	WP_160194596.1	ABC transporter permease	-
E3S88_RS11685 (E3S88_11685)	-	2331997..2332752 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
E3S88_RS11690 (E3S88_11690)	braS	2332860..2333747 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E3S88_RS11695 (E3S88_11695)	braR	2333758..2334423 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E3S88_RS11700 (E3S88_11700)	-	2334449..2334649 (-)	201	WP_000604725.1	hypothetical protein	-
E3S88_RS11705 (E3S88_11705)	-	2334847..2336271 (+)	1425	WP_124781558.1	alkaline phosphatase	-
E3S88_RS13925	-	2336331..2336432 (-)	102	WP_000731972.1	SE2200 family small protein	-
E3S88_RS11715 (E3S88_11715)	-	2336554..2337009 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E3S88_RS11720 (E3S88_11720)	-	2337254..2338015 (-)	762	WP_124781557.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=416399 E3S88_RS11690 WP_000143420.1 2332860..2333747(-) (braS) [Staphylococcus aureus strain UP_794]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=416399 E3S88_RS11690 WP_000143420.1 2332860..2333747(-) (braS) [Staphylococcus aureus strain UP_794]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTATTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAG
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993