Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E3S88_RS08635 Genome accession   NZ_CP047792
Coordinates   1724431..1725147 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain UP_794     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1719431..1730147
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S88_RS08610 (E3S88_08610) istA 1720126..1721418 (-) 1293 WP_124781593.1 IS21 family transposase -
  E3S88_RS13905 hld 1722020..1722100 (-) 81 WP_000046022.1 delta-hemolysin -
  E3S88_RS08620 (E3S88_08620) - 1722390..1722953 (+) 564 WP_001105699.1 accessory gene regulator AgrB -
  E3S88_RS08625 (E3S88_08625) agrD 1722956..1723099 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  E3S88_RS08630 (E3S88_08630) agrC 1723129..1724412 (+) 1284 WP_124781448.1 quorum-sensing sensor histidine kinase AgrC -
  E3S88_RS08635 (E3S88_08635) agrA 1724431..1725147 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  E3S88_RS08640 (E3S88_08640) - 1725219..1725326 (+) 108 WP_042900011.1 hypothetical protein -
  E3S88_RS08645 (E3S88_08645) - 1725515..1726474 (-) 960 WP_124781447.1 carbohydrate kinase family protein -
  E3S88_RS08650 (E3S88_08650) - 1726471..1727955 (-) 1485 WP_124781446.1 sucrose-6-phosphate hydrolase -
  E3S88_RS08655 (E3S88_08655) - 1728104..1729054 (-) 951 WP_124781445.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=416395 E3S88_RS08635 WP_000688492.1 1724431..1725147(+) (agrA) [Staphylococcus aureus strain UP_794]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=416395 E3S88_RS08635 WP_000688492.1 1724431..1725147(+) (agrA) [Staphylococcus aureus strain UP_794]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTAACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTCGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment