Detailed information NTG0416393

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: E3S88_RS07895
• Genome accession: NZ_CP047792
• Coordinates: 1597722..1598765 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UP_794
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1592722..1603765

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S88_RS07865 (E3S88_07865)	-	1593143..1594399 (-)	1257	WP_124780159.1	aminopeptidase	-
E3S88_RS07870 (E3S88_07870)	-	1594402..1594602 (-)	201	WP_000180460.1	DUF1128 family protein	-
E3S88_RS07875 (E3S88_07875)	-	1594749..1595213 (+)	465	WP_124780157.1	low molecular weight protein-tyrosine-phosphatase	-
E3S88_RS07880 (E3S88_07880)	-	1595220..1595495 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
E3S88_RS07885 (E3S88_07885)	-	1595773..1596990 (+)	1218	WP_124780155.1	YihY/virulence factor BrkB family protein	-
E3S88_RS07890 (E3S88_07890)	vraR	1597103..1597732 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
E3S88_RS07895 (E3S88_07895)	vraS	1597722..1598765 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
E3S88_RS07900 (E3S88_07900)	liaF	1598762..1599463 (-)	702	WP_124780153.1	cell wall-active antibiotics response protein LiaF	-
E3S88_RS07905 (E3S88_07905)	-	1599478..1599864 (-)	387	WP_001110179.1	hypothetical protein	-
E3S88_RS07910 (E3S88_07910)	map	1600081..1600839 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
E3S88_RS07915 (E3S88_07915)	-	1601252..1602238 (+)	987	WP_000999713.1	FUSC family protein	-
E3S88_RS07920 (E3S88_07920)	-	1602427..1602840 (-)	414	WP_124780151.1	hypothetical protein	-
E3S88_RS07925 (E3S88_07925)	-	1602869..1602979 (-)	111	WP_124780149.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=416393 E3S88_RS07895 WP_001017131.1 1597722..1598765(-) (vraS) [Staphylococcus aureus strain UP_794]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=416393 E3S88_RS07895 WP_001017131.1 1597722..1598765(-) (vraS) [Staphylococcus aureus strain UP_794]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAGTTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1