Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   E3S88_RS05935 Genome accession   NZ_CP047792
Coordinates   1222650..1223624 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain UP_794     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1217650..1228624
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S88_RS05895 (E3S88_05895) gcvT 1218151..1219242 (-) 1092 WP_124780615.1 glycine cleavage system aminomethyltransferase GcvT -
  E3S88_RS05900 (E3S88_05900) - 1219401..1219925 (-) 525 WP_001015120.1 shikimate kinase -
  E3S88_RS05905 (E3S88_05905) - 1219915..1220061 (-) 147 WP_001789879.1 hypothetical protein -
  E3S88_RS05910 (E3S88_05910) comGF 1220158..1220655 (-) 498 WP_001796472.1 competence type IV pilus minor pilin ComGF Machinery gene
  E3S88_RS05915 (E3S88_05915) comGE 1220573..1220872 (-) 300 WP_000844410.1 hypothetical protein Machinery gene
  E3S88_RS05920 (E3S88_05920) comGD 1220859..1221305 (-) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  E3S88_RS05925 (E3S88_05925) comGC 1221283..1221594 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  E3S88_RS05930 (E3S88_05930) comGB 1221608..1222678 (-) 1071 WP_124780613.1 competence type IV pilus assembly protein ComGB Machinery gene
  E3S88_RS05935 (E3S88_05935) comGA 1222650..1223624 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  E3S88_RS05940 (E3S88_05940) - 1223676..1224299 (-) 624 WP_001223003.1 MBL fold metallo-hydrolase -
  E3S88_RS05945 (E3S88_05945) - 1224296..1224625 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  E3S88_RS05950 (E3S88_05950) - 1224625..1225611 (-) 987 WP_000161315.1 ROK family glucokinase -
  E3S88_RS05955 (E3S88_05955) - 1225608..1225811 (-) 204 WP_124780611.1 YqgQ family protein -
  E3S88_RS05960 (E3S88_05960) - 1225792..1227255 (-) 1464 WP_001017867.1 rhomboid family protein -
  E3S88_RS05965 (E3S88_05965) - 1227267..1227806 (-) 540 WP_124780609.1 5-formyltetrahydrofolate cyclo-ligase -
  E3S88_RS05970 (E3S88_05970) rpmG 1228015..1228164 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=416381 E3S88_RS05935 WP_000697220.1 1222650..1223624(-) (comGA) [Staphylococcus aureus strain UP_794]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=416381 E3S88_RS05935 WP_000697220.1 1222650..1223624(-) (comGA) [Staphylococcus aureus strain UP_794]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAATTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTAATCAGAATTGTACCTCA
ATTTTTCCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment