Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E3S95_RS13725 Genome accession   NZ_CP047788
Coordinates   2796772..2797488 (-) Length   238 a.a.
NCBI ID   WP_160193969.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UP_1033     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2791772..2802488
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S95_RS13710 (E3S95_13710) - 2792859..2793809 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  E3S95_RS13715 (E3S95_13715) - 2793958..2795442 (+) 1485 WP_001791588.1 sucrose-6-phosphate hydrolase -
  E3S95_RS13720 (E3S95_13720) - 2795439..2796398 (+) 960 WP_001253292.1 carbohydrate kinase family protein -
  E3S95_RS13725 (E3S95_13725) agrA 2796772..2797488 (-) 717 WP_160193969.1 quorum-sensing response regulator AgrA Regulator
  E3S95_RS13730 (E3S95_13730) agrC 2797507..2798799 (-) 1293 WP_000387814.1 quorum-sensing sensor histidine kinase AgrC -
  E3S95_RS13735 (E3S95_13735) agrD 2798824..2798964 (-) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  E3S95_RS13740 (E3S95_13740) - 2798968..2799531 (-) 564 WP_001105709.1 accessory gene regulator AgrB -
  E3S95_RS14295 hld 2799821..2799901 (+) 81 WP_000046022.1 delta-hemolysin -
  E3S95_RS13750 (E3S95_13750) - 2800503..2801288 (-) 786 WP_000867948.1 carbon-nitrogen family hydrolase -
  E3S95_RS13755 (E3S95_13755) - 2801649..2802275 (-) 627 WP_000522388.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27904.92 Da        Isoelectric Point: 6.2996

>NTDB_id=416230 E3S95_RS13725 WP_160193969.1 2796772..2797488(-) (agrA) [Staphylococcus aureus strain UP_1033]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKQHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=416230 E3S95_RS13725 WP_160193969.1 2796772..2797488(-) (agrA) [Staphylococcus aureus strain UP_1033]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAACAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment