Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   H7790_RS04125 Genome accession   NZ_CP060645
Coordinates   812420..812896 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain TSPY1349     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 807420..817896
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7790_RS04100 (H7790_04130) - 807461..808249 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  H7790_RS04105 (H7790_04135) - 808289..809395 (+) 1107 WP_136073810.1 NAD(P)/FAD-dependent oxidoreductase -
  H7790_RS04110 (H7790_04140) rfbA 809453..810322 (+) 870 WP_111716814.1 glucose-1-phosphate thymidylyltransferase RfbA -
  H7790_RS04115 (H7790_04145) - 810322..810915 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  H7790_RS04120 (H7790_04150) rfbB 811159..812199 (+) 1041 WP_011284729.1 dTDP-glucose 4,6-dehydratase -
  H7790_RS04125 (H7790_04155) mutX 812420..812896 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  H7790_RS04130 (H7790_04160) - 812954..814135 (+) 1182 WP_115230555.1 AI-2E family transporter -
  H7790_RS04135 (H7790_04165) - 814125..815372 (+) 1248 WP_111713233.1 tetratricopeptide repeat protein -
  H7790_RS04140 (H7790_04170) fbp54 815431..817083 (-) 1653 WP_115230554.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=416166 H7790_RS04125 WP_002984880.1 812420..812896(+) (mutX) [Streptococcus pyogenes strain TSPY1349]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=416166 H7790_RS04125 WP_002984880.1 812420..812896(+) (mutX) [Streptococcus pyogenes strain TSPY1349]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAAGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACTTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703