Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E3T00_RS09630 Genome accession   NZ_CP047784
Coordinates   1976186..1976902 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain UP_1209     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1971186..1981902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3T00_RS09600 (E3T00_09600) - 1971402..1972028 (+) 627 WP_000522384.1 nitroreductase family protein -
  E3T00_RS09605 (E3T00_09605) - 1972389..1973174 (+) 786 WP_043044123.1 carbon-nitrogen family hydrolase -
  E3T00_RS13415 hld 1973774..1973854 (-) 81 WP_000046022.1 delta-hemolysin -
  E3T00_RS09615 (E3T00_09615) agrB 1974144..1974713 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  E3T00_RS09620 (E3T00_09620) agrD 1974710..1974850 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  E3T00_RS09625 (E3T00_09625) agrC 1974875..1976167 (+) 1293 WP_001789596.1 quorum-sensing sensor histidine kinase AgrC -
  E3T00_RS09630 (E3T00_09630) agrA 1976186..1976902 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  E3T00_RS09635 (E3T00_09635) - 1976974..1977083 (+) 110 Protein_1859 hypothetical protein -
  E3T00_RS09640 (E3T00_09640) - 1977271..1978230 (-) 960 WP_043044121.1 carbohydrate kinase family protein -
  E3T00_RS09645 (E3T00_09645) - 1978227..1979711 (-) 1485 WP_043044120.1 sucrose-6-phosphate hydrolase -
  E3T00_RS09650 (E3T00_09650) - 1979860..1980810 (-) 951 WP_043044119.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=416062 E3T00_RS09630 WP_000688492.1 1976186..1976902(+) (agrA) [Staphylococcus aureus strain UP_1209]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=416062 E3T00_RS09630 WP_000688492.1 1976186..1976902(+) (agrA) [Staphylococcus aureus strain UP_1209]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment