Detailed information NTG0416061

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: E3T00_RS09240
• Genome accession: NZ_CP047784
• Coordinates: 1899010..1900053 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UP_1209
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1894010..1905053

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3T00_RS09210 (E3T00_09210)	-	1894432..1895688 (-)	1257	WP_001793428.1	aminopeptidase	-
E3T00_RS09215 (E3T00_09215)	-	1895691..1895891 (-)	201	WP_000180460.1	DUF1128 family protein	-
E3T00_RS09220 (E3T00_09220)	-	1896038..1896502 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
E3T00_RS09225 (E3T00_09225)	-	1896509..1896784 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
E3T00_RS09230 (E3T00_09230)	-	1897062..1898279 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
E3T00_RS09235 (E3T00_09235)	vraR	1898391..1899020 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
E3T00_RS09240 (E3T00_09240)	vraS	1899010..1900053 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
E3T00_RS09245 (E3T00_09245)	liaF	1900050..1900751 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
E3T00_RS09250 (E3T00_09250)	-	1900766..1901152 (-)	387	WP_043044166.1	hypothetical protein	-
E3T00_RS09255 (E3T00_09255)	map	1901369..1902127 (-)	759	WP_000636138.1	type I methionyl aminopeptidase	-
E3T00_RS09260 (E3T00_09260)	-	1902658..1903644 (+)	987	WP_043044165.1	FUSC family protein	-
E3T00_RS09265 (E3T00_09265)	-	1904075..1904488 (-)	414	WP_001566709.1	hypothetical protein	-
E3T00_RS09270 (E3T00_09270)	-	1904517..1904627 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=416061 E3T00_RS09240 WP_001017131.1 1899010..1900053(-) (vraS) [Staphylococcus aureus strain UP_1209]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=416061 E3T00_RS09240 WP_001017131.1 1899010..1900053(-) (vraS) [Staphylococcus aureus strain UP_1209]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1