Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   H7792_RS08320 Genome accession   NZ_CP060643
Coordinates   1715025..1715792 (-) Length   255 a.a.
NCBI ID   WP_003058809.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY416     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1710025..1720792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7792_RS08305 (H7792_08275) hexB 1710534..1712516 (-) 1983 WP_228650343.1 DNA mismatch repair endonuclease MutL Machinery gene
  H7792_RS08310 (H7792_08280) - 1712611..1713762 (-) 1152 WP_014635780.1 tyrosine-type recombinase/integrase -
  H7792_RS08315 (H7792_08285) - 1714011..1714154 (+) 144 WP_011185066.1 putative holin-like toxin -
  H7792_RS08320 (H7792_08290) irvR 1715025..1715792 (-) 768 WP_003058809.1 helix-turn-helix transcriptional regulator Regulator
  H7792_RS08325 (H7792_08295) - 1715946..1716152 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  H7792_RS08820 (H7792_08300) - 1716186..1716952 (+) 767 Protein_1593 BRO family protein -
  H7792_RS08340 (H7792_08305) - 1716962..1717573 (+) 612 WP_228650346.1 Bro-N domain-containing protein -
  H7792_RS08345 (H7792_08310) - 1717594..1718001 (+) 408 WP_002992501.1 hypothetical protein -
  H7792_RS08770 - 1718014..1718136 (+) 123 WP_011285272.1 hypothetical protein -
  H7792_RS08350 (H7792_08315) - 1718419..1718940 (+) 522 WP_002992498.1 Rha family transcriptional regulator -
  H7792_RS08355 (H7792_08320) - 1719185..1719517 (+) 333 WP_111695052.1 hypothetical protein -
  H7792_RS08360 (H7792_08325) - 1719517..1719708 (+) 192 WP_010922764.1 hypothetical protein -
  H7792_RS08365 (H7792_08330) - 1719720..1720049 (+) 330 WP_136040345.1 hypothetical protein -
  H7792_RS08370 (H7792_08335) - 1720052..1720324 (+) 273 WP_001100459.1 hypothetical protein -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 28725.00 Da        Isoelectric Point: 4.3544

>NTDB_id=416022 H7792_RS08320 WP_003058809.1 1715025..1715792(-) (irvR) [Streptococcus pyogenes strain TSPY416]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide


Download         Length: 768 bp        

>NTDB_id=416022 H7792_RS08320 WP_003058809.1 1715025..1715792(-) (irvR) [Streptococcus pyogenes strain TSPY416]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(23-68)

Peptidase S24-like (Peptidase_S24)

(141-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

34

100

0.4

Multiple sequence alignment