Detailed information NTG0415997

Bioinformatically predicted

Overview

• Name: rexA
• Type: Machinery gene
• Locus tag: H7792_RS05825
• Genome accession: NZ_CP060643
• Coordinates: 1176487..1180116 (-)
• Length: 1209 a.a.
• NCBI ID: WP_323744188.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY416
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1171487..1185116

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7792_RS05800 (H7792_05795)	rpoD	1171664..1172773 (-)	1110	WP_002985187.1	RNA polymerase sigma factor RpoD	-
H7792_RS05805 (H7792_05800)	dnaG	1172782..1174551 (-)	1770	WP_228650397.1	DNA primase	-
H7792_RS05810 (H7792_05805)	mscL	1174727..1175089 (+)	363	WP_002990299.1	large conductance mechanosensitive channel protein MscL	-
H7792_RS05815 (H7792_05810)	rpsU	1175218..1175394 (-)	177	WP_000048058.1	30S ribosomal protein S21	-
H7792_RS05820 (H7792_05815)	-	1175535..1176347 (-)	813	WP_023078819.1	transporter substrate-binding domain-containing protein	-
H7792_RS05825 (H7792_05820)	rexA	1176487..1180116 (-)	3630	WP_323744188.1	helicase-exonuclease AddAB subunit AddA	Machinery gene
H7792_RS05830 (H7792_05825)	rexB	1180116..1183331 (-)	3216	WP_136283644.1	ATP-dependent nuclease subunit B	Machinery gene
H7792_RS05835 (H7792_05830)	-	1183482..1184399 (+)	918	WP_012560586.1	neutral zinc metallopeptidase	-

Sequence

Protein

• Length: 1209 a.a.
• Molecular weight: 138839.87 Da
• Isoelectric Point: 6.5516

>NTDB_id=415997 H7792_RS05825 WP_323744188.1 1176487..1180116(-) (rexA) [Streptococcus pyogenes strain TSPY416]
MSFAPFLSPEAIKHLQENERYSDQSQKRTAQQIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFT
VKAATELRERIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQFRIMQDKAEQDVLK
QEVFSKLFSEFMNQKEAPAFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDI
ELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTDLIPSGNDVT
VSKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESAFEFSDIAHFAIKILEENTDIR
QSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFR
SQSEALNVSNAVFSHLMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSEVTIVAKE
IIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKSVEVMVMLDTLRTINNPRNDYALVALLRSP
MFAFDEDDLARIALQKDNELDKDCLYDKIQRAVIGRGAYPELIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLIWKIFND
RFYFDFVASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQAVNLMTIHKSKGLQF
PYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVA
MTRAEKKVYFIGKASKSKSQDITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRLQ
TPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKATYEPLLEPIGVDIIEKSSRSLSDFTLP
HFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTLLDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYRE
APFAILKVDPISQEEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPVTKRYLVLMG
GGKPEIVEV

Nucleotide

• Length: 3630 bp

>NTDB_id=415997 H7792_RS05825 WP_323744188.1 1176487..1180116(-) (rexA) [Streptococcus pyogenes strain TSPY416]
ATTTCTTTTGCCCCATTTTTAAGCCCCGAAGCTATTAAACATTTACAAGAAAACGAAAGGTACAGTGATCAGTCTCAAAA
ACGCACAGCTCAACAAATTGAAGCAATTTATACTAGTGGCCAAAATATACTTGTATCAGCTTCTGCTGGTTCAGGAAAAA
CCTTTGTAATGGTCGAACGCATACTTGATAAAATTTTGAGAGGTGTTTCAATTGATCGGCTTTTTATCTCAACCTTTACT
GTTAAAGCAGCTACAGAACTGCGTGAACGGATTGAAAACAAATTATACTCACAAATTGCTCAAACTACAGATTTTCAAAT
GAAAGTTTATTTAACAGAACAATTGCAATCTCTTTGTCAAGCTGATATTGGTACTATGGATGCTTTTGCACAGAAAGTAG
TAAGTCGCTATGGTTATAGCATTGGCATTTCATCCCAATTTCGTATCATGCAGGATAAAGCAGAACAAGATGTTTTAAAG
CAAGAGGTGTTTAGCAAACTCTTTAGTGAGTTTATGAATCAAAAAGAGGCACCGGCGTTTAGGGCTCTTGTGAAAAATTT
TTCTGGTAACTGTAAAGACACTTCAGCTTTTAGAGAGTTAGTTTATACTTGTTATTCTTTTAGCCAATCGACAGAAAATC
CAAAAATATGGTTGCAAGAAAATTTTCTAAGCGCTGCTAAAACTTACCAAAGACTTGAAGATATCCCGGATCATGATATT
GAACTCTTACTTTTGGCAATGCAAGACACTGCAAATCAGCTAAGAGATGTGACTGATATGGAAGATTATGGGCAGCTGAC
TAAGGCAGGTAGCCGATCTGCTAAATACACTAAACACTTAACGATCATAGAAAAGTTGTCTGATTGGGTGCGTGATTTTA
AATGTTTGTATGGAAAAGCCGGATTGGATCGGTTGATCAGAGATGTGACAGACCTTATACCATCTGGGAATGATGTTACA
GTCTCGAAGGTAAAATACCCTGTTTTTAAGACCTTGCATCAAAAATTAAAACAATTTAGGCATTTAGAAACAATTTTAAT
GTATCAGAAAGACTGTTTTCCCTTATTGGAACAGTTACAAGATTTTGTGCTTGCGTTTTCAGAAGCTTATTTAGCTGTCA
AAATACAAGAAAGCGCTTTTGAATTTTCAGATATTGCACACTTTGCAATCAAAATTTTAGAGGAAAATACGGATATTCGC
CAATCCTATCAGCAACACTATCATGAGGTGATGGTTGATGAATATCAAGATAACAATCATATGCAAGAGCGACTCCTGAC
CTTACTATCGAACGGTCATAATCGCTTTATGGTAGGAGATATCAAACAATCGATCTATCGATTTCGGCAAGCCGATCCTC
AGATTTTTAATCAAAAGTTTAGAGACTATCAAAAAAAACCTGAGCAGGGGAAAGTGATTTTACTCAAAGAAAACTTTCGT
AGCCAATCAGAGGCGTTAAATGTCAGCAATGCTGTTTTTAGTCACTTAATGGACGAATCAGTAGGAGACGTCTTATACGA
TGAGCAACATCAGTTAATAGCAGGTAGTCATGCTCAAACAGTCCCCTATCTAGACCGTCGTGCTCAGTTATTGCTATATA
ATAGCGATAAAGATGATGGCAACGCCCCTTCAGATAGTGAGGGTATTTCATTTAGTGAGGTTACAATTGTTGCCAAAGAA
ATTATTAAGCTTCACAATGATAAGGGTGTCCCTTTTGAAGACATTACGTTACTCGTTTCTTCAAGAACAAGAAATGATAT
CATTTCTCATACATTCAATCAATATGGTATTCCTATAGTAACAGATGGTGGGCAGCAAAACTATCTTAAATCTGTTGAAG
TGATGGTTATGTTAGATACATTACGCACCATTAATAACCCAAGAAATGATTATGCCCTTGTGGCTTTACTGCGCTCACCG
ATGTTTGCCTTTGATGAGGATGATTTAGCAAGAATAGCACTTCAAAAAGACAATGAGCTAGATAAAGATTGCCTATATGA
CAAGATACAAAGGGCTGTGATTGGAAGAGGTGCTTATCCTGAATTGATCCACGATACCTTGCTTGGCAAGTTAAATGTTT
TTTTAAAGACGTTGAAAAGCTGGCGTCGATACGCTAAGCTAGGGTCGTTGTATGACTTGATTTGGAAAATTTTCAATGAT
CGTTTTTATTTTGATTTTGTAGCTAGTCAAGCAAAAGCAGAACAAGCACAAGCTAATCTATACGCATTAGCTCTACGTGC
TAATCAGTTTGAAAAATCGGGCTATAAAGGGCTATACCGTTTTATTAAAATGATTGATAAGGTACTTGAGACGCAAAATG
ACTTAGCAGATGTGGAAGTGGCTGCTCCTAAACAAGCTGTTAATTTAATGACCATTCACAAGTCTAAAGGTTTACAATTT
CCGTATGTATTTATCCTTAATTGTGACAAGCGCTTCTCAATGACAGATATTCATAAATCATTTATTCTGAATCGGCAGCA
CGGTATCGGTATCAAGTACCTTGCAGATATCAAAGGTTTACTTGGTGAAACAACACTCAATTCTGTTAAAGTAAGCATGG
AAACCTTACCTTATCAATTGAACAAACAAGAGTTGCGCTTAGCAACTTTATCAGAACAAATGCGCTTACTGTATGTTGCT
ATGACACGAGCTGAAAAAAAAGTTTATTTTATTGGTAAAGCTAGTAAGAGCAAAAGTCAAGATATCACAGATCCTAAAAA
GTTAGGCAAACTTTTGCCGCTGGCTTTACGAGAACAGTTATTGACATTCCAAGATTGGCTATTAGCAATAGCAGATATAT
TTTCAACTGAAGATCTTTATTTTGATGTTCGCTTTATTGAAGATAGTGATTTGACACAAGAGTCAGTCGGACGACTTCAA
ACACCACAGTTATTAAATCCAGATGATCTTAAAGATAATCGTCAATCAGAAACAATTGCACGGGCTTTAGATATGTTAGA
AGCAGTGTCTCAATTGAATGCCAATTATGAAGCAGCTATTCATTTGCCAACAGTTCGAACTCCTAGCCAACTTAAGGCAA
CTTACGAGCCTTTATTAGAACCCATTGGTGTAGATATTATAGAGAAATCTTCTCGATCGCTATCTGATTTTACTTTGCCA
CATTTTTCAAAAAAAGCAAAAGTTGAAGCAAGTCATATTGGATCAGCTCTTCATCAGTTGATGCAGGTGCTCCCTTTGTC
AAAACCGATAAATCAACAAACGCTTTTAGACGCTTTAAGAGGAATTGATAGTAACGAAGAGGTAAAAACAGCTCTTGATC
TCAAAAAAATAGAGTCGTTCTTTTGTGATACAAGCCTAGGCCAATTTTTTCAGACTTACCAAAAACACTTGTATCGAGAA
GCGCCATTTGCTATTTTAAAAGTTGACCCTATTAGTCAAGAAGAATATGTCCTACGTGGTATTATAGATGCCTACTTTTT
GTTTGATGATCATATTGTATTAGTGGACTATAAAACAGATAAATACAAGCAGCCCATTGAGTTAAAAAAGCGTTACCAAC
AACAGTTGGAGTTATATGCAGAAGCTCTCACTCAAACGTATAAACTTCCTGTGACTAAGCGCTATCTTGTTTTAATGGGA
GGTGGAAAGCCAGAAATTGTCGAAGTTTAA

Domains

Predicted by InterProScan.

• UvrD/REP helicase N-terminal domain (UvrD-helicase) (29-463)

• UvrD-like helicase C-terminal domain (UvrD_C) (473-891)

• PD-(D/E)XK nuclease superfamily (PDDEXK_1) (1045-1196)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
rexA	Streptococcus pneumoniae R6	48.29	100	0.49