Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   H7792_RS03250 Genome accession   NZ_CP060643
Coordinates   646626..647288 (+) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain TSPY416     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 641626..652288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7792_RS03230 (H7792_03215) - 642500..644500 (+) 2001 WP_136284869.1 potassium transporter Kup -
  H7792_RS03235 (H7792_03220) - 644524..644802 (-) 279 WP_011017953.1 GIY-YIG nuclease family protein -
  H7792_RS03240 (H7792_03225) - 644792..645568 (-) 777 WP_002994360.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  H7792_RS03245 (H7792_03230) - 645686..646426 (+) 741 WP_012560804.1 lysophospholipid acyltransferase family protein -
  H7792_RS03250 (H7792_03235) comEA/celA/cilE 646626..647288 (+) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  H7792_RS03255 (H7792_03240) - 647269..649511 (+) 2243 Protein_584 DNA internalization-related competence protein ComEC/Rec2 -
  H7792_RS03260 (H7792_03245) holA 649582..650622 (+) 1041 WP_011888795.1 DNA polymerase III subunit delta -
  H7792_RS03265 (H7792_03250) sodA 650719..651324 (+) 606 WP_002983977.1 superoxide dismutase SodA -
  H7792_RS03270 (H7792_03255) - 651491..651718 (+) 228 WP_030126413.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=415980 H7792_RS03250 WP_002995626.1 646626..647288(+) (comEA/celA/cilE) [Streptococcus pyogenes strain TSPY416]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=415980 H7792_RS03250 WP_002995626.1 646626..647288(+) (comEA/celA/cilE) [Streptococcus pyogenes strain TSPY416]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405