Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   H7793_RS03980 Genome accession   NZ_CP060642
Coordinates   755175..755837 (+) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain TSPY1312     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 750175..760837
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7793_RS03960 (H7793_03960) - 751049..753049 (+) 2001 WP_111703219.1 potassium transporter Kup -
  H7793_RS03965 (H7793_03965) - 753073..753351 (-) 279 WP_011017953.1 GIY-YIG nuclease family protein -
  H7793_RS03970 (H7793_03970) - 753341..754117 (-) 777 WP_002994360.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  H7793_RS03975 (H7793_03975) - 754235..754975 (+) 741 WP_168389440.1 lysophospholipid acyltransferase family protein -
  H7793_RS03980 (H7793_03980) comEA/celA/cilE 755175..755837 (+) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  H7793_RS03985 (H7793_03985) comEC/celB 755818..758061 (+) 2244 WP_136021582.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  H7793_RS03990 (H7793_03990) holA 758132..759172 (+) 1041 WP_002989176.1 DNA polymerase III subunit delta -
  H7793_RS03995 (H7793_03995) sodA 759269..759874 (+) 606 WP_002983977.1 superoxide dismutase SodA -
  H7793_RS04000 (H7793_04000) - 760041..760196 (+) 156 WP_002989180.1 hypothetical protein -
  H7793_RS04005 (H7793_04005) - 760252..760500 (+) 249 WP_002989183.1 serine hydrolase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=415887 H7793_RS03980 WP_002995626.1 755175..755837(+) (comEA/celA/cilE) [Streptococcus pyogenes strain TSPY1312]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=415887 H7793_RS03980 WP_002995626.1 755175..755837(+) (comEA/celA/cilE) [Streptococcus pyogenes strain TSPY1312]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405