Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   H7795_RS05360 Genome accession   NZ_CP060641
Coordinates   1055933..1056409 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain TSPY210     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1050933..1061409
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7795_RS05345 (H7795_05325) fbp54 1051746..1053398 (+) 1653 WP_014407524.1 Rqc2 family fibronectin-binding protein Fbp54 -
  H7795_RS05350 (H7795_05330) - 1053457..1054704 (-) 1248 WP_023613187.1 tetratricopeptide repeat protein -
  H7795_RS05355 (H7795_05335) - 1054694..1055875 (-) 1182 WP_023613223.1 AI-2E family transporter -
  H7795_RS05360 (H7795_05340) mutX 1055933..1056409 (-) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  H7795_RS05365 (H7795_05345) speh 1057013..1057723 (-) 711 WP_012560660.1 streptococcal pyrogenic exotoxin SpeH -
  H7795_RS05370 (H7795_05350) - 1057929..1058216 (-) 288 WP_002993613.1 hypothetical protein -
  H7795_RS05375 (H7795_05355) - 1058382..1059134 (-) 753 WP_023613198.1 CHAP domain-containing protein -
  H7795_RS05380 (H7795_05360) - 1059252..1059707 (-) 456 WP_011184730.1 phage holin family protein -
  H7795_RS05385 (H7795_05365) - 1059717..1060328 (-) 612 WP_023613176.1 DUF1366 domain-containing protein -
  H7795_RS05390 (H7795_05370) - 1060325..1060762 (-) 438 WP_023613191.1 DUF1617 family protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=415804 H7795_RS05360 WP_002984880.1 1055933..1056409(-) (mutX) [Streptococcus pyogenes strain TSPY210]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=415804 H7795_RS05360 WP_002984880.1 1055933..1056409(-) (mutX) [Streptococcus pyogenes strain TSPY210]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703