Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   H7796_RS05340 Genome accession   NZ_CP060640
Coordinates   1088882..1089544 (-) Length   220 a.a.
NCBI ID   WP_228631239.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY764     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1083882..1094544
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7796_RS05315 (H7796_05330) - 1084219..1084467 (-) 249 WP_002989183.1 serine hydrolase -
  H7796_RS05320 (H7796_05335) - 1084523..1084678 (-) 156 WP_002989180.1 hypothetical protein -
  H7796_RS05325 (H7796_05340) sodA 1084845..1085450 (-) 606 WP_020905299.1 superoxide dismutase SodA -
  H7796_RS05330 (H7796_05345) holA 1085547..1086587 (-) 1041 WP_020905300.1 DNA polymerase III subunit delta -
  H7796_RS05335 (H7796_05350) comEC/celB 1086658..1088901 (-) 2244 WP_136268042.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  H7796_RS05340 (H7796_05355) comEA/celA/cilE 1088882..1089544 (-) 663 WP_228631239.1 ComEA family DNA-binding protein Machinery gene
  H7796_RS05345 (H7796_05360) - 1089744..1090484 (-) 741 WP_012560804.1 lysophospholipid acyltransferase family protein -
  H7796_RS05350 (H7796_05365) - 1090602..1091378 (+) 777 WP_002994360.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  H7796_RS05355 (H7796_05370) - 1091368..1091646 (+) 279 WP_228631240.1 GIY-YIG nuclease family protein -
  H7796_RS05360 (H7796_05375) - 1091670..1093670 (-) 2001 WP_228631241.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24637.48 Da        Isoelectric Point: 6.7451

>NTDB_id=415704 H7796_RS05340 WP_228631239.1 1088882..1089544(-) (comEA/celA/cilE) [Streptococcus pyogenes strain TSPY764]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKIH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=415704 H7796_RS05340 WP_228631239.1 1088882..1089544(-) (comEA/celA/cilE) [Streptococcus pyogenes strain TSPY764]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGATTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.512

94.091

0.4