Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ETEC_RS21485 Genome accession   NC_017633
Coordinates   4274715..4275305 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli ETEC H10407     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4269715..4280305
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETEC_RS21470 (ETEC_3960) uhpT 4270355..4271746 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  ETEC_RS21475 (ETEC_3961) uhpC 4271884..4273203 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  ETEC_RS21480 (ETEC_3962) uhpB 4273213..4274715 (-) 1503 WP_014640043.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  ETEC_RS21485 (ETEC_3963) letA 4274715..4275305 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  ETEC_RS21490 (ETEC_3964) ilvN 4275381..4275671 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  ETEC_RS21495 (ETEC_3965) ilvB 4275675..4277363 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  ETEC_RS21500 (ETEC_3966) ivbL 4277469..4277567 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  ETEC_RS21515 tisB 4278132..4278221 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  ETEC_RS31575 ysdE 4278345..4278419 (-) 75 WP_211180519.1 protein YsdE -
  ETEC_RS21520 (ETEC_3967) emrD 4278501..4279685 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  ETEC_RS21525 (ETEC_3968) yidF 4279693..4280190 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=41501 ETEC_RS21485 WP_000633668.1 4274715..4275305(-) (letA) [Escherichia coli ETEC H10407]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=41501 ETEC_RS21485 WP_000633668.1 4274715..4275305(-) (letA) [Escherichia coli ETEC H10407]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment