Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF   Type   Machinery gene
Locus tag   GQ601_RS12940 Genome accession   NZ_CP047646
Coordinates   2674904..2675401 (+) Length   165 a.a.
NCBI ID   WP_001825340.1    Uniprot ID   A0A2S6DDC2
Organism   Staphylococcus aureus strain 19/Msa0875     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2669904..2680401
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQ601_RS12900 (GQ601_12960) - 2669984..2670970 (+) 987 WP_000161315.1 ROK family glucokinase -
  GQ601_RS12905 (GQ601_12965) - 2670970..2671299 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  GQ601_RS12910 (GQ601_12970) - 2671296..2671919 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  GQ601_RS12915 (GQ601_12975) comGA 2671971..2672909 (+) 939 WP_212593115.1 GspE/PulE family protein Machinery gene
  GQ601_RS12920 (GQ601_12980) comGB 2672881..2673951 (+) 1071 WP_000776425.1 competence type IV pilus assembly protein ComGB Machinery gene
  GQ601_RS12925 (GQ601_12985) comGC 2673965..2674276 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  GQ601_RS12930 (GQ601_12990) comGD 2674254..2674700 (+) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  GQ601_RS12935 (GQ601_12995) comGE 2674687..2674986 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  GQ601_RS12940 (GQ601_13000) comGF 2674904..2675401 (+) 498 WP_001825340.1 competence type IV pilus minor pilin ComGF Machinery gene
  GQ601_RS12945 (GQ601_13005) - 2675498..2675644 (+) 147 WP_001789879.1 hypothetical protein -
  GQ601_RS12950 (GQ601_13010) - 2675634..2676158 (+) 525 WP_001015120.1 shikimate kinase -
  GQ601_RS12955 (GQ601_13015) gcvT 2676317..2677408 (+) 1092 WP_031811291.1 glycine cleavage system aminomethyltransferase GcvT -
  GQ601_RS12960 (GQ601_13020) gcvPA 2677428..2678774 (+) 1347 WP_000019698.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
  GQ601_RS12965 (GQ601_13025) gcvPB 2678767..2680239 (+) 1473 WP_000202179.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPB -

Sequence

Protein


Download         Length: 165 a.a.        Molecular weight: 19179.92 Da        Isoelectric Point: 10.2192

>NTDB_id=414955 GQ601_RS12940 WP_001825340.1 2674904..2675401(+) (comGF) [Staphylococcus aureus strain 19/Msa0875]
MILSKVTNKFVLFQKIPLLIKRHVYSINVKAFSLIEMLVAMMVISITLLIVPDLIRLSKTFLIESRELTTVDFEFFSRDI
LEDFKGVDRNDIEIRQQRIILHKGEEMIEYKLINNKIIKVVNDRGNITLINNVTAFTANIYYKSIIKITITVKVGTNLQT
KTIYV

Nucleotide


Download         Length: 498 bp        

>NTDB_id=414955 GQ601_RS12940 WP_001825340.1 2674904..2675401(+) (comGF) [Staphylococcus aureus strain 19/Msa0875]
ATGATATTAAGCAAAGTGACCAACAAATTTGTGCTATTTCAAAAAATACCACTTCTTATCAAAAGACATGTATACAGTAT
TAATGTCAAAGCTTTTTCGCTTATTGAAATGTTAGTAGCGATGATGGTTATAAGCATAACTTTACTAATTGTTCCAGACT
TAATTAGACTTAGCAAAACTTTTCTAATTGAAAGTAGGGAATTAACAACTGTAGATTTCGAATTTTTCTCAAGAGATATT
CTAGAGGATTTTAAAGGTGTAGATAGAAACGATATTGAAATTAGGCAACAGCGTATCATTTTACATAAAGGTGAAGAAAT
GATCGAATACAAATTAATAAATAATAAAATTATTAAAGTTGTAAATGACAGAGGAAATATAACATTGATTAATAATGTTA
CAGCATTTACTGCAAATATCTACTATAAATCTATTATTAAAATAACGATAACAGTTAAAGTCGGTACAAATCTGCAGACT
AAAACTATTTATGTATAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(28-51)

Putative Competence protein ComGF (ComGF)

(68-155)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DDC2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF Staphylococcus aureus N315

98.182

100

0.982
  comGF Staphylococcus aureus MW2

96.97

100

0.97

Multiple sequence alignment