Detailed information NTG0414938

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: GQ601_RS11090
• Genome accession: NZ_CP047646
• Coordinates: 2328226..2329269 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 19/Msa0875
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2323226..2334269

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GQ601_RS11060 (GQ601_11110)	-	2323841..2323951 (+)	111	WP_014937049.1	hypothetical protein	-
GQ601_RS11065 (GQ601_11115)	-	2323980..2324393 (+)	414	WP_025174370.1	hypothetical protein	-
GQ601_RS11070 (GQ601_11120)	-	2324582..2325568 (-)	987	WP_000999712.1	aromatic acid exporter family protein	-
GQ601_RS11075 (GQ601_11125)	map	2326152..2326910 (+)	759	WP_000636145.1	type I methionyl aminopeptidase	-
GQ601_RS11080 (GQ601_11130)	-	2327127..2327513 (+)	387	WP_001110182.1	hypothetical protein	-
GQ601_RS11085 (GQ601_11135)	liaF	2327528..2328229 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
GQ601_RS11090 (GQ601_11140)	vraS	2328226..2329269 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
GQ601_RS11095 (GQ601_11145)	vraR	2329259..2329888 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
GQ601_RS11100 (GQ601_11150)	-	2330001..2331218 (-)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
GQ601_RS11105 (GQ601_11155)	-	2331496..2331771 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
GQ601_RS11110 (GQ601_11160)	-	2331778..2332242 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
GQ601_RS11115 (GQ601_11165)	-	2332389..2332589 (+)	201	WP_000180460.1	DUF1128 family protein	-
GQ601_RS11120 (GQ601_11170)	-	2332592..2333848 (+)	1257	WP_074347694.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=414938 GQ601_RS11090 WP_001017131.1 2328226..2329269(+) (vraS) [Staphylococcus aureus strain 19/Msa0875]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=414938 GQ601_RS11090 WP_001017131.1 2328226..2329269(+) (vraS) [Staphylococcus aureus strain 19/Msa0875]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1