Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   HMPREF0833_RS04845 Genome accession   NC_015678
Coordinates   1022825..1023538 (+) Length   237 a.a.
NCBI ID   WP_013903973.1    Uniprot ID   -
Organism   Streptococcus parasanguinis ATCC 15912     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1023674..1044526 1022825..1023538 flank 136
IS/Tn 1023674..1024138 1022825..1023538 flank 136


Gene organization within MGE regions


Location: 1022825..1044526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0833_RS04845 (HMPREF0833_10982) treR 1022825..1023538 (+) 714 WP_013903973.1 trehalose operon repressor Regulator
  HMPREF0833_RS04850 (HMPREF0833_10983) tnpA 1023674..1024138 (-) 465 WP_041818345.1 IS200/IS605 family transposase -
  HMPREF0833_RS04855 (HMPREF0833_10984) - 1024479..1025282 (-) 804 WP_003005034.1 ABC transporter ATP-binding protein -
  HMPREF0833_RS04860 (HMPREF0833_10985) - 1025292..1026185 (-) 894 WP_013903975.1 ABC transporter permease -
  HMPREF0833_RS04865 (HMPREF0833_10986) - 1026196..1027173 (-) 978 WP_013903976.1 ABC transporter substrate-binding protein -
  HMPREF0833_RS04870 (HMPREF0833_10987) - 1027582..1028931 (-) 1350 WP_037608034.1 hemolysin family protein -
  HMPREF0833_RS04875 (HMPREF0833_10988) - 1029549..1031024 (-) 1476 WP_013903978.1 M protein trans-acting positive regulator PRD domain-containing protein -
  HMPREF0833_RS04880 (HMPREF0833_10989) - 1031158..1032285 (-) 1128 WP_013903979.1 AI-2E family transporter -
  HMPREF0833_RS04885 (HMPREF0833_10991) - 1032689..1033648 (-) 960 WP_013903981.1 hypothetical protein -
  HMPREF0833_RS04890 (HMPREF0833_10992) - 1033648..1034067 (-) 420 WP_013903982.1 Panacea domain-containing protein -
  HMPREF0833_RS04895 (HMPREF0833_10993) - 1034379..1034795 (-) 417 WP_013903983.1 DUF1492 domain-containing protein -
  HMPREF0833_RS04900 (HMPREF0833_10994) - 1034819..1035244 (-) 426 WP_174260430.1 hypothetical protein -
  HMPREF0833_RS04905 (HMPREF0833_10995) - 1035301..1035681 (-) 381 WP_041818494.1 hypothetical protein -
  HMPREF0833_RS04910 (HMPREF0833_10996) - 1035728..1036336 (-) 609 WP_013903986.1 hypothetical protein -
  HMPREF0833_RS10900 (HMPREF0833_10997) - 1036439..1036600 (-) 162 WP_013903987.1 hypothetical protein -
  HMPREF0833_RS04915 (HMPREF0833_10998) - 1036642..1036803 (-) 162 WP_306420058.1 hypothetical protein -
  HMPREF0833_RS04920 (HMPREF0833_10999) - 1036827..1037303 (-) 477 WP_013903989.1 hypothetical protein -
  HMPREF0833_RS04925 (HMPREF0833_11000) - 1037728..1038957 (-) 1230 WP_013903990.1 AAA family ATPase -
  HMPREF0833_RS10905 (HMPREF0833_11001) - 1038961..1039116 (-) 156 WP_013903991.1 hypothetical protein -
  HMPREF0833_RS04930 (HMPREF0833_11002) - 1039109..1039384 (-) 276 WP_013903992.1 hypothetical protein -
  HMPREF0833_RS04935 (HMPREF0833_11003) - 1039377..1039718 (-) 342 WP_013903993.1 hypothetical protein -
  HMPREF0833_RS04940 (HMPREF0833_11004) - 1039715..1039930 (-) 216 WP_013903994.1 hypothetical protein -
  HMPREF0833_RS04945 (HMPREF0833_11005) - 1039932..1040132 (-) 201 WP_013903995.1 hypothetical protein -
  HMPREF0833_RS04950 (HMPREF0833_11006) - 1040399..1041025 (-) 627 WP_013903996.1 Rha family transcriptional regulator -
  HMPREF0833_RS04955 (HMPREF0833_11007) - 1041044..1041238 (-) 195 WP_000794674.1 helix-turn-helix transcriptional regulator -
  HMPREF0833_RS04960 (HMPREF0833_11008) - 1041455..1041982 (+) 528 WP_013903997.1 helix-turn-helix domain-containing protein -
  HMPREF0833_RS04965 (HMPREF0833_11009) - 1042027..1043016 (+) 990 WP_013903998.1 DUF3644 domain-containing protein -
  HMPREF0833_RS04970 (HMPREF0833_11010) - 1043360..1044526 (+) 1167 WP_013903999.1 site-specific integrase -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27689.74 Da        Isoelectric Point: 8.6694

>NTDB_id=41383 HMPREF0833_RS04845 WP_013903973.1 1022825..1023538(+) (treR) [Streptococcus parasanguinis ATCC 15912]
MKKYQQIYQILKEQILEEKYLVGDFLPSENDLKEHYQVSRDTIRKSLNLLQEEGFIKTVQGMGSQICRQAHFDFPVSQLT
SYQEIVKASGLRSETNVIRLEKISIDEKGAKKTGFPLHRLVWKVTRQRVVDGVASVLDIDYLDRELIPGLTKEIAQHSIY
QYIEEDLKLQIGYAKKEILISPIDNRDKILLDLGKDQHVVTVRSQVHLADGRQFQFTESRHKLDKFHFVDYAERRKS

Nucleotide


Download         Length: 714 bp        

>NTDB_id=41383 HMPREF0833_RS04845 WP_013903973.1 1022825..1023538(+) (treR) [Streptococcus parasanguinis ATCC 15912]
ATGAAAAAATACCAACAAATCTATCAAATTTTAAAAGAACAAATACTAGAAGAAAAATATCTAGTCGGGGATTTTCTGCC
TAGCGAGAACGACTTAAAAGAGCACTACCAGGTCAGTCGAGATACCATCCGTAAGTCCCTCAATCTCTTGCAGGAGGAAG
GCTTTATCAAGACTGTTCAAGGAATGGGATCGCAAATTTGTAGGCAAGCTCACTTTGACTTCCCTGTTTCCCAATTAACC
AGCTATCAAGAAATCGTCAAAGCTTCTGGTCTTCGCTCAGAAACTAATGTCATTCGTTTGGAAAAGATCAGTATTGATGA
AAAAGGAGCTAAAAAGACAGGCTTCCCCCTTCACCGTTTGGTTTGGAAAGTAACCCGACAACGGGTAGTGGATGGCGTCG
CTTCTGTCTTAGATATTGATTACCTAGACAGAGAGCTGATCCCTGGCCTAACCAAGGAAATTGCCCAGCACTCTATCTAC
CAATATATAGAAGAAGACTTGAAATTGCAGATTGGCTATGCAAAGAAAGAAATTTTGATTTCACCAATCGATAATCGCGA
CAAAATCTTACTGGATCTTGGAAAAGACCAACACGTGGTAACGGTCCGTTCCCAAGTTCACTTAGCAGACGGACGCCAAT
TCCAGTTCACCGAAAGCCGACACAAATTAGACAAGTTTCATTTTGTCGACTATGCAGAGCGGAGGAAATCATGA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-64)

UTRA domain (UTRA)

(89-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

57.627

99.578

0.574

Multiple sequence alignment