Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   H6X75_RS10060 Genome accession   NZ_CP060156
Coordinates   1988398..1989351 (-) Length   317 a.a.
NCBI ID   WP_000345117.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700608     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1983398..1994351
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H6X75_RS10035 (H6X75_10025) - 1984159..1984782 (-) 624 WP_000932655.1 hypothetical protein -
  H6X75_RS10040 (H6X75_10030) jag 1984833..1985819 (-) 987 WP_000260025.1 RNA-binding cell elongation regulator Jag/EloR -
  H6X75_RS10045 (H6X75_10035) - 1985838..1986662 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  H6X75_RS10050 (H6X75_10040) rnpA 1986637..1987008 (-) 372 WP_000739246.1 ribonuclease P protein component -
  H6X75_RS11300 - 1987025..1987156 (-) 132 WP_000768904.1 hypothetical protein -
  H6X75_RS10055 (H6X75_10045) - 1987157..1988347 (-) 1191 WP_000167766.1 acetate kinase -
  H6X75_RS10060 (H6X75_10050) comGH 1988398..1989351 (-) 954 WP_000345117.1 class I SAM-dependent methyltransferase Machinery gene
  H6X75_RS10065 (H6X75_10055) - 1989412..1990005 (-) 594 Protein_1971 methyltransferase domain-containing protein -
  H6X75_RS10070 (H6X75_10060) comGG/cglG 1990142..1990555 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  H6X75_RS10075 (H6X75_10065) comGF/cglF 1990533..1990994 (-) 462 WP_000250530.1 competence type IV pilus minor pilin ComGF Machinery gene
  H6X75_RS10080 (H6X75_10070) comGE/cglE 1990957..1991259 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  H6X75_RS10085 (H6X75_10075) comGD/cglD 1991222..1991626 (-) 405 WP_000588006.1 competence type IV pilus minor pilin ComGD Machinery gene
  H6X75_RS10090 (H6X75_10080) comGC/cglC 1991619..1991945 (-) 327 WP_000738638.1 comG operon protein ComGC Machinery gene
  H6X75_RS10095 (H6X75_10085) comGB/cglB 1991947..1992963 (-) 1017 WP_075270915.1 competence type IV pilus assembly protein ComGB Machinery gene
  H6X75_RS10100 (H6X75_10090) comGA/cglA/cilD 1992911..1993852 (-) 942 WP_000249556.1 competence type IV pilus ATPase ComGA Machinery gene
  H6X75_RS10105 (H6X75_10095) - 1993927..1994292 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35719.88 Da        Isoelectric Point: 4.2434

>NTDB_id=413563 H6X75_RS10060 WP_000345117.1 1988398..1989351(-) (comGH) [Streptococcus pneumoniae strain PZ900700608]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGET
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGFKYLKSDGYAIFLAPSDLLTSPQ
SDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=413563 H6X75_RS10060 WP_000345117.1 1988398..1989351(-) (comGH) [Streptococcus pneumoniae strain PZ900700608]
ATGGATTTTGAAAAAATTGAACAAGCCTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGGAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGTCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGTTTAAGTACCTCAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA140

53.994

98.738

0.533
  comGH Streptococcus mutans UA159

53.674

98.738

0.53