Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   H6X75_RS05485 Genome accession   NZ_CP060156
Coordinates   1095498..1095962 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain PZ900700608     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1090498..1100962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H6X75_RS05465 (H6X75_05455) - 1091449..1092417 (-) 969 WP_000105363.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  H6X75_RS05470 (H6X75_05460) pdrM 1092571..1093932 (-) 1362 WP_000278526.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  H6X75_RS05475 (H6X75_05465) - 1093943..1094203 (-) 261 WP_001105925.1 hypothetical protein -
  H6X75_RS05480 (H6X75_05470) - 1094217..1095485 (-) 1269 WP_000924508.1 dihydroorotase -
  H6X75_RS05485 (H6X75_05475) mutX 1095498..1095962 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  H6X75_RS05490 (H6X75_05480) - 1095972..1096625 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  H6X75_RS05495 (H6X75_05485) - 1096763..1097410 (-) 648 WP_001813281.1 hypothetical protein -
  H6X75_RS05500 (H6X75_05490) - 1097424..1098137 (-) 714 WP_000499432.1 YjjG family noncanonical pyrimidine nucleotidase -
  H6X75_RS05505 (H6X75_05495) dhaM 1098597..1098977 (-) 381 WP_000443785.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=413515 H6X75_RS05485 WP_001135768.1 1095498..1095962(-) (mutX) [Streptococcus pneumoniae strain PZ900700608]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=413515 H6X75_RS05485 WP_001135768.1 1095498..1095962(-) (mutX) [Streptococcus pneumoniae strain PZ900700608]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987