Detailed information NTG0412621

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: GSF72_RS04520
• Genome accession: NZ_CP047321
• Coordinates: 898211..899254 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain RJ1267
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 893211..904254

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GSF72_RS04490 (GSF72_04490)	-	893581..893691 (+)	111	WP_001790257.1	hypothetical protein	-
GSF72_RS04495 (GSF72_04495)	-	893720..894133 (+)	414	WP_001549145.1	hypothetical protein	-
GSF72_RS04500 (GSF72_04500)	-	894564..895550 (-)	987	WP_000999713.1	FUSC family protein	-
GSF72_RS04505 (GSF72_04505)	map	896137..896895 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
GSF72_RS04510 (GSF72_04510)	-	897112..897498 (+)	387	WP_001110179.1	hypothetical protein	-
GSF72_RS04515 (GSF72_04515)	liaF	897513..898214 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
GSF72_RS04520 (GSF72_04520)	vraS	898211..899254 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
GSF72_RS04525 (GSF72_04525)	vraR	899244..899873 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
GSF72_RS04530 (GSF72_04530)	-	899989..901206 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
GSF72_RS04535 (GSF72_04535)	-	901484..901759 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
GSF72_RS04540 (GSF72_04540)	-	901766..902230 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
GSF72_RS04545 (GSF72_04545)	-	902377..902577 (+)	201	WP_000180461.1	DUF1128 family protein	-
GSF72_RS04550 (GSF72_04550)	-	902580..903836 (+)	1257	WP_001795438.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=412621 GSF72_RS04520 WP_001017131.1 898211..899254(+) (vraS) [Staphylococcus aureus strain RJ1267]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=412621 GSF72_RS04520 WP_001017131.1 898211..899254(+) (vraS) [Staphylococcus aureus strain RJ1267]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1