Detailed information    

insolico Bioinformatically predicted

Overview

Name   cqsS   Type   Regulator
Locus tag   GTF74_RS16270 Genome accession   NZ_CP047304
Coordinates   455722..457782 (+) Length   686 a.a.
NCBI ID   WP_001882375.1    Uniprot ID   Q9KM66
Organism   Vibrio cholerae O1 biovar El Tor strain E7946     
Function   autoinducer sensor (predicted from homology)   
Competence regulation

Genomic Context

Location: 450722..462782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GTF74_RS16260 (GTF74_16300) - 451443..452582 (+) 1140 WP_000670244.1 exonuclease SbcCD subunit D -
  GTF74_RS16265 (GTF74_16305) - 452584..455625 (+) 3042 WP_001247622.1 SMC family ATPase -
  GTF74_RS16270 (GTF74_16310) cqsS 455722..457782 (+) 2061 WP_001882375.1 quorum-sensing CAI-1 autoinducer sensor kinase/phosphatase CqsS Regulator
  GTF74_RS16275 (GTF74_16315) cqsA 458011..459180 (-) 1170 WP_001039912.1 alpha-hydroxyketone-type quorum-sensing autoinducer synthase Regulator
  GTF74_RS16280 (GTF74_16320) - 459377..460339 (-) 963 WP_001104009.1 TDT family transporter -
  GTF74_RS16285 (GTF74_16325) clcA 460486..461892 (-) 1407 WP_000107451.1 H(+)/Cl(-) exchange transporter ClcA -

Sequence

Protein


Download         Length: 686 a.a.        Molecular weight: 78382.17 Da        Isoelectric Point: 5.3891

>NTDB_id=412485 GTF74_RS16270 WP_001882375.1 455722..457782(+) (cqsS) [Vibrio cholerae O1 biovar El Tor strain E7946]
MIVSMDVIKRVYQYAEPNLSLVGWMGMLGFPAYYFIWEYWFPQSYENLGLRCAAAVLFGGLVFRDSMPKKWQRYMPGYFL
FTIGFCLPFFFAFMMLMNDWSTIWAMSFMASIFLHILLVHDTRVMALQALFSVLVAYLAVYGLTDFHPTTLIEWQYIPIF
LFTYVFGNLCFFRNQISHETKVSIAKTFGAGIAHEMRNPLSALKTSIDVVRTMIPKPQTAAHTDYSLDAQELDLLHQILN
EADDVIYSGNNAIDLLLTSIDENRVSPASFKKHSVVDVIEKAVKTFPYKNAADQHSVELEVHQPFDFFGSDTLLTYALFN
LLKNAFYYQKEHFSVCISIEQTSEHNLIRVRDNGVGIAPEMLEDIFRDFYTFGKNGSYGLGLPFCRKVMSAFGGTIRCAS
QQGQWTEFVLSFPRYDSDTVNEIKTELLKTKSLIYIGSNQAIVRELNQLAVEDEFGFTAISAQQAVRRQDYEFEFDLILL
DLDDATAQGELLPKLEGTLSFAEGCIGYVYDPGKTYAVNINRYLRIQPISIHSILRKPRKIIERLLFEQESLSMNRNVIP
LQKSRHERRILVVDDNQSIRTFTAILLEQQGYEVVQANDGSEVLKHMESQNIDLVLMDIEMPNVGGLEATRLIRNSEHEY
KNIPIIGYTGDNSPKTLALVQTSGMNDFIVKPADRDVLLNKVAAWV

Nucleotide


Download         Length: 2061 bp        

>NTDB_id=412485 GTF74_RS16270 WP_001882375.1 455722..457782(+) (cqsS) [Vibrio cholerae O1 biovar El Tor strain E7946]
GTGATAGTGAGCATGGATGTAATAAAGAGAGTGTATCAATACGCAGAACCTAATCTGTCCTTAGTCGGATGGATGGGCAT
GCTTGGCTTTCCTGCCTACTACTTCATCTGGGAATATTGGTTTCCGCAATCTTACGAAAATTTAGGGCTGCGTTGTGCGG
CAGCGGTGCTGTTCGGTGGGCTGGTGTTTCGTGATTCGATGCCTAAGAAATGGCAGCGGTATATGCCGGGCTATTTTTTA
TTCACCATAGGTTTCTGCTTACCCTTTTTCTTCGCTTTTATGATGTTAATGAATGACTGGTCGACAATTTGGGCCATGTC
GTTTATGGCGTCCATTTTTCTGCATATTCTCTTAGTACACGATACGAGAGTGATGGCGTTACAAGCACTTTTCTCTGTGT
TGGTGGCCTATCTTGCGGTATATGGTTTGACGGATTTTCACCCGACGACTTTGATTGAATGGCAATACATACCGATCTTT
TTGTTTACTTATGTATTTGGGAATTTATGTTTTTTCCGTAACCAAATCTCTCATGAGACCAAAGTGTCGATTGCCAAAAC
GTTCGGAGCGGGGATTGCCCATGAAATGCGTAATCCACTCAGCGCTTTGAAAACGTCGATTGATGTTGTGCGAACCATGA
TCCCTAAACCGCAAACTGCAGCTCATACGGATTATTCCTTGGATGCGCAAGAGCTGGATCTGCTGCATCAAATTTTGAAT
GAAGCTGATGATGTCATCTACTCTGGCAATAACGCGATTGATTTGCTGCTCACCTCGATTGATGAAAACCGTGTCTCTCC
GGCGAGTTTTAAAAAACACTCAGTGGTAGATGTGATTGAAAAAGCAGTGAAAACTTTTCCGTATAAAAATGCAGCGGACC
AGCACTCGGTAGAGCTTGAAGTGCATCAGCCGTTTGACTTTTTTGGCAGTGATACTCTACTGACTTATGCGCTATTTAAC
CTGTTGAAAAATGCCTTCTATTACCAAAAAGAGCATTTCTCGGTTTGTATTTCCATTGAACAAACCAGTGAGCATAACCT
TATTCGAGTCCGTGATAACGGTGTGGGGATTGCGCCAGAGATGTTGGAAGACATTTTCCGTGATTTCTATACCTTCGGTA
AAAATGGTAGCTATGGGCTAGGATTGCCATTTTGCCGCAAAGTGATGTCCGCATTTGGGGGGACGATTCGCTGTGCGTCT
CAACAAGGTCAATGGACAGAATTCGTATTGAGCTTTCCTCGTTACGATTCCGATACGGTTAACGAGATAAAAACAGAACT
GCTGAAAACCAAATCGCTCATTTATATCGGCTCAAATCAAGCTATCGTTCGAGAGTTAAATCAGCTCGCAGTAGAAGATG
AGTTTGGTTTTACCGCTATTTCTGCGCAGCAAGCAGTAAGACGCCAAGATTATGAGTTTGAGTTCGACCTTATTTTGCTC
GACCTTGATGACGCTACGGCGCAGGGAGAACTACTGCCGAAACTTGAAGGGACATTGAGTTTTGCAGAAGGCTGTATCGG
CTATGTGTATGATCCGGGCAAAACGTATGCAGTAAACATTAACCGTTATCTGCGTATCCAACCGATCAGTATTCACTCTA
TTCTCAGAAAGCCGCGGAAAATCATCGAACGCTTGTTGTTTGAGCAAGAATCCTTATCGATGAATCGTAACGTGATCCCC
TTGCAAAAGAGTCGGCATGAACGACGTATTTTGGTGGTTGACGATAATCAATCGATCCGAACTTTTACGGCTATTTTGCT
TGAGCAACAAGGTTATGAAGTGGTGCAAGCCAACGATGGTAGTGAAGTGCTCAAGCATATGGAGAGTCAAAACATCGATT
TAGTATTGATGGACATTGAAATGCCGAATGTCGGGGGATTAGAAGCGACGCGTTTAATTCGTAACTCTGAGCATGAGTAC
AAAAATATTCCGATCATTGGTTACACCGGTGATAACAGCCCCAAAACCTTGGCTCTGGTACAAACCTCTGGCATGAATGA
TTTCATTGTGAAGCCTGCTGACCGTGATGTATTGCTAAATAAAGTGGCAGCTTGGGTGTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(570-682)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(312-413)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9KM66

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cqsS Vibrio cholerae strain A1552

100

100

1

Multiple sequence alignment