Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   H4986_RS00135 Genome accession   NZ_CP059971
Coordinates   22436..24238 (-) Length   600 a.a.
NCBI ID   WP_146314468.1    Uniprot ID   -
Organism   Campylobacter jejuni strain C34     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 17436..29238
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H4986_RS00110 (H4986_00110) - 17561..18760 (+) 1200 WP_002853994.1 MFS transporter -
  H4986_RS00115 (H4986_00115) ciaC 18816..19136 (+) 321 WP_002873153.1 invasion antigen CiaC -
  H4986_RS00120 (H4986_00120) hemE 19320..20342 (+) 1023 WP_041160173.1 uroporphyrinogen decarboxylase -
  H4986_RS00125 (H4986_00125) - 20339..21241 (+) 903 WP_041160174.1 radical SAM protein -
  H4986_RS00130 (H4986_00130) - 21238..22434 (-) 1197 WP_052789981.1 hypothetical protein -
  H4986_RS00135 (H4986_00135) uvrC 22436..24238 (-) 1803 WP_146314468.1 excinuclease ABC subunit UvrC Machinery gene
  H4986_RS00140 (H4986_00140) - 24231..24725 (-) 495 WP_002869076.1 hypothetical protein -
  H4986_RS00145 (H4986_00145) guaA 24864..26399 (+) 1536 WP_052789979.1 glutamine-hydrolyzing GMP synthase -
  H4986_RS00150 (H4986_00150) - 26485..27945 (+) 1461 WP_002853236.1 hypothetical protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69804.85 Da        Isoelectric Point: 9.3081

>NTDB_id=412071 H4986_RS00135 WP_146314468.1 22436..24238(-) (uvrC) [Campylobacter jejuni strain C34]
MTKENLENELKTLPNSTGVYQYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPRNSLRIQKMIEETVHLEFIATNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
ASCKSPCIFYQISRCLAPCDKRISKEKYLEILDEAMHALLNPSILIKNLEKQMLVLAQNENYEEAAKVRDQIVTIKDLEV
KVEMDIAKLEDFEVFALAFEDSMLSTLRFVVQNGKIISANSKITPIKNDIQWDQNEIYKQLILENFSMDIPLLANVIYVY
EEFEDRVLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKFYFELENLPNDIEIFDNS
HLQGVANVGAMVTYRINSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKALLDLAKEIIVSSGAN
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLKSSKLANLGLS
SGVIQKLLAYYGNFESIYKADFKDLTMLVGRKVAQKIKEN

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=412071 H4986_RS00135 WP_146314468.1 22436..24238(-) (uvrC) [Campylobacter jejuni strain C34]
TTGACTAAAGAGAATTTAGAAAATGAGCTAAAAACTCTTCCCAATAGTACTGGCGTTTATCAATACTTCAATCAAGAAGG
AAAGCTTTTATATGTAGGTAAGGCTAAAAATCTTAAAAATCGTGTCAAATCTTATTTTGCCTTTACTCCAAATTTACATG
CAAATCCAAGAAATTCTTTAAGAATTCAAAAAATGATTGAAGAAACAGTGCATTTGGAATTTATTGCTACTAATTCAGAG
GCTGATGCTTTGATTTTGGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTGCTAAGAGATGATAAAAC
TTATCCTTATATTTATGTGGATTTTGAAGAAGAATTTCCACGCTTTGAGATCACTAGAAAATTAGTAAAAAAAAGCAAAA
TTAAATATTTTGGCCCTTTTTTTAAAGGCGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCTTTAAAACAAAAA
GCAAGTTGTAAATCCCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCACCTTGTGATAAACGCATCAGCAAAGAAAA
ATACCTTGAAATTTTAGATGAGGCTATGCACGCGCTTTTAAATCCTAGTATTTTAATAAAAAATTTAGAAAAACAAATGC
TTGTTTTAGCACAGAATGAAAATTACGAAGAAGCAGCTAAAGTAAGAGATCAGATTGTAACGATTAAGGATTTAGAAGTT
AAGGTTGAAATGGATATTGCAAAATTAGAAGATTTTGAAGTGTTTGCTTTAGCTTTTGAAGATTCTATGCTTTCAACCTT
GCGTTTTGTGGTGCAAAATGGAAAAATTATCAGTGCAAATTCTAAAATTACTCCTATAAAAAATGATATACAATGGGATC
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGCATGGATATTCCTTTGCTTGCAAATGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAGTGCTTTTAGAAGAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAGAATTTGTGATTTGGCTTTTCAAAATGCCCTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTTTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGACAATTCT
CATTTGCAAGGCGTGGCAAATGTTGGAGCTATGGTAACTTATAGAATAAATTCTTGGGATAAGTCAAAATATAGAAAATT
TCATTTAAAACATAAAAATGACTATGATCAAATGCGTGAAGTTTTAACGCGTAGGGCTTTGGACTTTGATAAAATACCTC
CTCCTGATTTATGGCTTATAGATGGGGGAAAGGCTTTGCTTGATTTGGCTAAAGAAATCATTGTAAGTAGTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGAGCTAAAGGAGGTGCTAAGGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGTCTAAGTATTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCACACC
GTTTTGCTATTAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAAAAGTTCTAAGCTTGCAAATTTAGGACTTAGT
TCAGGGGTTATACAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTACAAT
GCTTGTAGGCAGGAAAGTGGCGCAAAAGATAAAGGAAAATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-236)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-537)

GIY-YIG catalytic domain (GIY-YIG)

(18-99)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

46.387

99.167

0.46