Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   H4990_RS03770 Genome accession   NZ_CP059969
Coordinates   725239..727041 (+) Length   600 a.a.
NCBI ID   WP_002859308.1    Uniprot ID   -
Organism   Campylobacter jejuni strain C109     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 720239..732041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H4990_RS03755 (H4990_03755) - 721532..722992 (-) 1461 WP_002853236.1 hypothetical protein -
  H4990_RS03760 (H4990_03760) guaA 723078..724613 (-) 1536 WP_002859310.1 glutamine-hydrolyzing GMP synthase -
  H4990_RS03765 (H4990_03765) - 724752..725246 (+) 495 WP_002859309.1 hypothetical protein -
  H4990_RS03770 (H4990_03770) uvrC 725239..727041 (+) 1803 WP_002859308.1 excinuclease ABC subunit UvrC Machinery gene
  H4990_RS03775 (H4990_03775) - 727043..728239 (+) 1197 WP_002859307.1 hypothetical protein -
  H4990_RS03780 (H4990_03780) - 728236..729138 (-) 903 WP_002859306.1 radical SAM protein -
  H4990_RS03785 (H4990_03785) hemE 729135..730157 (-) 1023 WP_002859305.1 uroporphyrinogen decarboxylase -
  H4990_RS03790 (H4990_03790) ciaC 730341..730661 (-) 321 WP_002853224.1 invasion antigen CiaC -
  H4990_RS03795 (H4990_03795) - 730717..731916 (-) 1200 WP_002853994.1 MFS transporter -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69679.78 Da        Isoelectric Point: 9.4413

>NTDB_id=411999 H4990_RS03770 WP_002859308.1 725239..727041(+) (uvrC) [Campylobacter jejuni strain C109]
MTKENLENELKTLPNSTGVYQYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPRNSLRIQKMIEETVHLEFIATNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDVLYLYYPLKQK
ASCKSPCIFYQISRCLAPCDKLISKEKYLEILDEAIHALLNPSVLLKNLEKQMLVLAQNENYEEAAKVRDQIAMIKDLEV
KVEIDIAKLEDFEVFALAFKNSVLSTLRFVVQNGKIISANSKITPIKNDIQWDQNEIYKQLILENFSMDIPLLANVIYVY
EEFEDRVLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKFYFELENLPNDIEIFDNS
HLQGVANVGAMVTYRINSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKALLDLAKEIIVSSGAN
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLKSSKLANLGLS
SGVIQKLLAYYGNFESIYKADFKDLTMLVGRKAAQKIKEN

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=411999 H4990_RS03770 WP_002859308.1 725239..727041(+) (uvrC) [Campylobacter jejuni strain C109]
TTGACTAAAGAGAATTTAGAAAATGAGTTAAAAACTCTTCCTAATAGTACTGGCGTTTATCAATACTTCAATCAAGAAGG
AAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAATCGTGTCAAATCTTATTTTGCCTTTACTCCAAATTTACATG
CAAATCCAAGAAATTCTTTAAGAATTCAAAAAATGATTGAAGAAACAGTGCATTTGGAATTTATTGCTACTAATTCAGAG
GCTGATGCTTTGATTTTAGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTGCTAAGAGATGATAAAAC
TTATCCTTATATTTATGTGGATTTTGAAGAAGAATTTCCACGCTTTGAGATCACTAGAAAATTAGTAAAAAAAAGCAAAA
TTAAATATTTTGGCCCTTTTTTTAAAGGCGCTAGAGAGCTTTTAGATGTGCTTTATTTATACTATCCTTTAAAGCAAAAA
GCAAGTTGTAAATCCCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAACTCATCAGCAAAGAAAA
ATACCTTGAAATTTTAGATGAGGCTATACACGCACTTTTAAATCCTAGTGTTTTGCTTAAAAACTTAGAAAAACAAATGC
TTGTTTTAGCACAAAATGAAAATTACGAAGAAGCAGCTAAAGTAAGAGATCAGATTGCAATGATTAAAGATTTGGAAGTT
AAGGTTGAAATAGATATTGCGAAATTAGAAGATTTTGAAGTATTTGCTTTAGCTTTTAAAAATTCCGTGCTTTCAACCTT
GCGTTTTGTGGTGCAAAATGGAAAAATTATCAGTGCAAATTCTAAGATTACTCCTATAAAAAATGATATACAATGGGATC
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGCATGGATATTCCTTTGCTTGCAAATGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAGTGCTTTTAGAAGAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAGAATTTGTGATTTGGCTTTTCAAAATGCCCTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTTTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGACAATTCT
CATTTGCAAGGCGTGGCAAATGTTGGAGCTATGGTAACTTATAGAATAAATTCTTGGGATAAGTCAAAATATAGAAAATT
TCATTTAAAACATAAAAATGACTATGATCAAATGCGTGAAGTTTTAACGCGTAGGGCTTTGGACTTTGATAAAATACCTC
CTCCTGATTTATGGCTTATAGATGGGGGAAAGGCTTTGCTTGATTTGGCTAAAGAAATCATTGTAAGTAGTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGAGCTAAAGGAGGTGCTAAGGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGTCTAAGTATTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCACACC
GTTTTGCTATTAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAAAAGTTCTAAGCTTGCAAATTTAGGACTTAGT
TCAGGGGTTATACAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTACAAT
GCTTGTAGGCAGGAAAGCGGCGCAAAAGATAAAGGAAAATTGA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(18-99)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-537)

UvrB/uvrC motif (UVR)

(205-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

47.251

97

0.458